BDBM50138669 6-Carbamimidoyl-naphthalene-2-carboxylic acid (1-isobutyl-1,2,3,4-tetrahydro-isoquinolin-7-yl)-amide::CHEMBL109535

SMILES CC(C)CC1NCCc2ccc(NC(=O)c3ccc4cc(ccc4c3)C(N)=N)cc12

InChI Key InChIKey=GQMKJIVMMQHGLX-UHFFFAOYSA-N

Data  6 KI

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
Find this compound or compounds like it in BindingDB:
   Substructure
Similarity at least:  must be >=0.5
Exact match

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 6 hits for monomerid = 50138669   

TargetSerine protease 1(Human)
Abbott Laboratories

Curated by ChEMBL
LigandPNGBDBM50138669(6-Carbamimidoyl-naphthalene-2-carboxylic acid (1-i...)
Affinity DataKi:  115nMAssay Description:Binding affinity against porcine trypsin was determined.More data for this Ligand-Target Pair
In Depth
Date in BDB:
11/10/2009
Entry Details Article
PubMed
TargetUrokinase-type plasminogen activator(Human)
Abbott Laboratories

Curated by ChEMBL
LigandPNGBDBM50138669(6-Carbamimidoyl-naphthalene-2-carboxylic acid (1-i...)
Affinity DataKi:  123nMAssay Description:Binding affinity to human urokinase-type plasminogen activator (microPa).More data for this Ligand-Target Pair
In Depth
Date in BDB:
11/10/2009
Entry Details Article
PubMed
TargetPlasminogen(Human)
Abbott Laboratories

Curated by ChEMBL
LigandPNGBDBM50138669(6-Carbamimidoyl-naphthalene-2-carboxylic acid (1-i...)
Affinity DataKi:  1.19E+3nMAssay Description:Binding affinity towards human plasmin.More data for this Ligand-Target Pair
In Depth
Date in BDB:
11/10/2009
Entry Details Article
PubMed
TargetPlasma kallikrein(Human)
Abbott Laboratories

Curated by ChEMBL
LigandPNGBDBM50138669(6-Carbamimidoyl-naphthalene-2-carboxylic acid (1-i...)
Affinity DataKi:  1.35E+3nMAssay Description:Binding affinity against human plasma kallikrein.More data for this Ligand-Target Pair
In Depth
Date in BDB:
11/10/2009
Entry Details Article
PubMed
TargetProthrombin(Human)
Abbott Laboratories

Curated by ChEMBL
LigandPNGBDBM50138669(6-Carbamimidoyl-naphthalene-2-carboxylic acid (1-i...)
Affinity DataKi:  7.31E+3nMAssay Description:Binding affinity against human alpha thrombin.More data for this Ligand-Target Pair
In Depth
Date in BDB:
11/10/2009
Entry Details Article
PubMed
TargetTissue-type plasminogen activator(Human)
Abbott Laboratories

Curated by ChEMBL
LigandPNGBDBM50138669(6-Carbamimidoyl-naphthalene-2-carboxylic acid (1-i...)
Affinity DataKi: >5.00E+4nMAssay Description:Binding affinity towards human Tissue type plasminogen activator.More data for this Ligand-Target Pair
In Depth
Date in BDB:
11/10/2009
Entry Details Article
PubMed