BDBM50138649 8-Methyl-3-p-tolyl-2-(3-p-tolyl-isoxazol-5-yl)-8-aza-bicyclo[3.2.1]octane::CHEMBL103867

SMILES CN1C2CCC1C(C(C2)c1ccc(C)cc1)c1cc(no1)-c1ccc(C)cc1

InChI Key InChIKey=IQNHMRJZPKQKFD-UHFFFAOYSA-N

Data  3 IC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
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Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 3 hits for monomerid = 50138649   

TargetTransporter(Rat)
Research Triangle Institute

Curated by ChEMBL
LigandPNGBDBM50138649(8-Methyl-3-p-tolyl-2-(3-p-tolyl-isoxazol-5-yl)-8-a...)
Affinity DataIC50: 1.00E+5nMAssay Description:Binding affinity towards norepinephrine transporter was determined by using [3H]nisoxetine radioligandMore data for this Ligand-Target Pair
In Depth
Date in BDB:
11/30/2012
Entry Details Article
PubMed
TargetSodium-dependent serotonin transporter(Rat)
Research Triangle Institute

Curated by ChEMBL
LigandPNGBDBM50138649(8-Methyl-3-p-tolyl-2-(3-p-tolyl-isoxazol-5-yl)-8-a...)
Affinity DataIC50: 1.00E+5nMAssay Description:Inhibitory concentration required to inhibit serotonin transporter 5-HTT was determined by using [3H]paroxetine radioligandMore data for this Ligand-Target Pair
In Depth
Date in BDB:
11/30/2012
Entry Details Article
PubMed
TargetSodium-dependent dopamine transporter(Rat)
Research Triangle Institute

Curated by ChEMBL
LigandPNGBDBM50138649(8-Methyl-3-p-tolyl-2-(3-p-tolyl-isoxazol-5-yl)-8-a...)
Affinity DataIC50: 13nMAssay Description:Inhibitory concentration required to inhibit dopamine transporter DAT was determined by using [3H]WIN-35428 radioligandMore data for this Ligand-Target Pair
In Depth
Date in BDB:
11/30/2012
Entry Details Article
PubMed