BDBM50138611 CHEMBL150614::N-(9-Ethyl-9H-carbazol-3-yl)-2-{4-[(R)-2-hydroxy-3-(2-methyl-benzothiazol-5-yloxy)-propyl]-piperazin-1-yl}-acetamide

SMILES CCn1c2ccccc2c2cc(NC(=O)CN3CCN(C[C@@H](O)COc4ccc5sc(C)nc5c4)CC3)ccc12

InChI Key InChIKey=WYMUHCAWPDYRJQ-UHFFFAOYSA-N

Data  4 IC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
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Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 4 hits for monomerid = 50138611   

TargetPeroxisomal acyl-coenzyme A oxidase 1(Rat)
Cv Therapeutics

Curated by ChEMBL
LigandPNGBDBM50138611(N-(9-Ethyl-9H-carbazol-3-yl)-2-{4-[(R)-2-hydroxy-3...)
Affinity DataIC50: 850nMAssay Description:Inhibitory activity against Palmitoyl-CoA oxidase to inhibit rat heart mitochondrial Palmitoyl-CoA oxidation.More data for this Ligand-Target Pair
In Depth
Date in BDB:
11/10/2009
Entry Details Article
PubMed
TargetCytochrome P450 3A4(Human)
Cv Therapeutics

Curated by ChEMBL
LigandPNGBDBM50138611(N-(9-Ethyl-9H-carbazol-3-yl)-2-{4-[(R)-2-hydroxy-3...)
Affinity DataIC50: 3.90E+4nMAssay Description:Inhibition of cytochrome P450 3A4 of isolated guinea pig heartMore data for this Ligand-Target Pair
In Depth
Date in BDB:
11/10/2009
Entry Details Article
PubMed
TargetCytochrome P450 2C9(Human)
Cv Therapeutics

Curated by ChEMBL
LigandPNGBDBM50138611(N-(9-Ethyl-9H-carbazol-3-yl)-2-{4-[(R)-2-hydroxy-3...)
Affinity DataIC50: 1.00E+5nMAssay Description:Inhibition of cytochrome P450 2C9 of isolated guinea pig heartMore data for this Ligand-Target Pair
In Depth
Date in BDB:
11/10/2009
Entry Details Article
PubMed
TargetCytochrome P450 1A2(Human)
Cv Therapeutics

Curated by ChEMBL
LigandPNGBDBM50138611(N-(9-Ethyl-9H-carbazol-3-yl)-2-{4-[(R)-2-hydroxy-3...)
Affinity DataIC50: 1.00E+5nMAssay Description:Inhibition of cytochrome P450 1A2 of isolated guinea pig heartMore data for this Ligand-Target Pair
In Depth
Date in BDB:
11/10/2009
Entry Details Article
PubMed