BDBM50138157 Biphenyl-4-carboxylic acid {1-[(5-aminomethyl-2-chloro-phenylcarbamoyl)-methyl]-2-oxo-azepan-3-yl}-amide::CHEMBL323783

SMILES NCc1ccc(Cl)c(NC(=O)CN2CCCCC(NC(=O)c3ccc(cc3)-c3ccccc3)C2=O)c1

InChI Key InChIKey=JTDHGVJBDFRZDP-UHFFFAOYSA-N

Data  8 IC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
Find this compound or compounds like it in BindingDB:
   Substructure
Similarity at least:  must be >=0.5
Exact match

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 8 hits for monomerid = 50138157   

TargetTissue-type plasminogen activator(Human)
The Bristol-Myers Squibb Pharmaceutical Research Institute

Curated by ChEMBL
LigandPNGBDBM50138157(Biphenyl-4-carboxylic acid {1-[(5-aminomethyl-2-ch...)
Affinity DataIC50: 870nMAssay Description:Compound was tested for inhibition of human tissue type plasminogen activatorMore data for this Ligand-Target Pair
In Depth
Date in BDB:
11/10/2009
Entry Details Article
PubMed
TargetPlasminogen(Human)
The Bristol-Myers Squibb Pharmaceutical Research Institute

Curated by ChEMBL
LigandPNGBDBM50138157(Biphenyl-4-carboxylic acid {1-[(5-aminomethyl-2-ch...)
Affinity DataIC50: 330nMAssay Description:Compound was tested for inhibition of human plasminMore data for this Ligand-Target Pair
In Depth
Date in BDB:
11/10/2009
Entry Details Article
PubMed
TargetVitamin K-dependent protein C(Human)
The Bristol-Myers Squibb Pharmaceutical Research Institute

Curated by ChEMBL
LigandPNGBDBM50138157(Biphenyl-4-carboxylic acid {1-[(5-aminomethyl-2-ch...)
Affinity DataIC50: 870nMAssay Description:Compound was tested for inhibition of human activated protein C (APC)More data for this Ligand-Target Pair
In Depth
Date in BDB:
11/10/2009
Entry Details Article
PubMed
TargetProthrombin(Human)
The Bristol-Myers Squibb Pharmaceutical Research Institute

Curated by ChEMBL
LigandPNGBDBM50138157(Biphenyl-4-carboxylic acid {1-[(5-aminomethyl-2-ch...)
Affinity DataIC50: 870nMAssay Description:Compound was tested for inhibition of human alpha-thrombin (FIIa)More data for this Ligand-Target Pair
In Depth
Date in BDB:
11/10/2009
Entry Details Article
PubMed
TargetUrokinase-type plasminogen activator(Human)
The Bristol-Myers Squibb Pharmaceutical Research Institute

Curated by ChEMBL
LigandPNGBDBM50138157(Biphenyl-4-carboxylic acid {1-[(5-aminomethyl-2-ch...)
Affinity DataIC50: 870nMAssay Description:Compound was tested for inhibition of human urokinase-type plasminogen activatorMore data for this Ligand-Target Pair
In Depth
Date in BDB:
11/10/2009
Entry Details Article
PubMed
TargetSerine protease 1(Human)
The Bristol-Myers Squibb Pharmaceutical Research Institute

Curated by ChEMBL
LigandPNGBDBM50138157(Biphenyl-4-carboxylic acid {1-[(5-aminomethyl-2-ch...)
Affinity DataIC50: 360nMAssay Description:Compound was tested for inhibition of human trypsinMore data for this Ligand-Target Pair
In Depth
Date in BDB:
11/10/2009
Entry Details Article
PubMed
TargetCoagulation factor X(Human)
The Bristol-Myers Squibb Pharmaceutical Research Institute

Curated by ChEMBL
LigandPNGBDBM50138157(Biphenyl-4-carboxylic acid {1-[(5-aminomethyl-2-ch...)
Affinity DataIC50: 870nMAssay Description:Compound was tested for inhibition of human Coagulation factor XMore data for this Ligand-Target Pair
In Depth
Date in BDB:
11/10/2009
Entry Details Article
PubMed
TargetTryptase beta-2/delta/gamma(Human)
The Bristol-Myers Squibb Pharmaceutical Research Institute

Curated by ChEMBL
LigandPNGBDBM50138157(Biphenyl-4-carboxylic acid {1-[(5-aminomethyl-2-ch...)
Affinity DataIC50: 38nMAssay Description:Inhibition of human tryptase.More data for this Ligand-Target Pair
In Depth
Date in BDB:
11/10/2009
Entry Details Article
PubMed