BDBM50138154 Biphenyl-4-carboxylic acid {1-[(5-aminomethyl-2-methyl-phenylcarbamoyl)-methyl]-2-oxo-azepan-3-yl}-amide::CHEMBL104064

SMILES Cc1ccc(CN)cc1NC(=O)CN1CCCCC(NC(=O)c2ccc(cc2)-c2ccccc2)C1=O

InChI Key InChIKey=BVTOALZLIBJPNB-UHFFFAOYSA-N

Data  8 IC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
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Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 8 hits for monomerid = 50138154   

TargetCoagulation factor X(Human)
The Bristol-Myers Squibb Pharmaceutical Research Institute

Curated by ChEMBL
LigandPNGBDBM50138154(Biphenyl-4-carboxylic acid {1-[(5-aminomethyl-2-me...)
Affinity DataIC50: 450nMAssay Description:Compound was tested for inhibition of human Coagulation factor XMore data for this Ligand-Target Pair
In Depth
Date in BDB:
11/10/2009
Entry Details Article
PubMed
TargetProthrombin(Human)
The Bristol-Myers Squibb Pharmaceutical Research Institute

Curated by ChEMBL
LigandPNGBDBM50138154(Biphenyl-4-carboxylic acid {1-[(5-aminomethyl-2-me...)
Affinity DataIC50: 450nMAssay Description:Compound was tested for inhibition of human alpha-thrombin (FIIa)More data for this Ligand-Target Pair
In Depth
Date in BDB:
11/10/2009
Entry Details Article
PubMed
TargetTissue-type plasminogen activator(Human)
The Bristol-Myers Squibb Pharmaceutical Research Institute

Curated by ChEMBL
LigandPNGBDBM50138154(Biphenyl-4-carboxylic acid {1-[(5-aminomethyl-2-me...)
Affinity DataIC50: 450nMAssay Description:Compound was tested for inhibition of human tissue type plasminogen activatorMore data for this Ligand-Target Pair
In Depth
Date in BDB:
11/10/2009
Entry Details Article
PubMed
TargetUrokinase-type plasminogen activator(Human)
The Bristol-Myers Squibb Pharmaceutical Research Institute

Curated by ChEMBL
LigandPNGBDBM50138154(Biphenyl-4-carboxylic acid {1-[(5-aminomethyl-2-me...)
Affinity DataIC50: 450nMAssay Description:Compound was tested for inhibition of human urokinase-type plasminogen activatorMore data for this Ligand-Target Pair
In Depth
Date in BDB:
11/10/2009
Entry Details Article
PubMed
TargetVitamin K-dependent protein C(Human)
The Bristol-Myers Squibb Pharmaceutical Research Institute

Curated by ChEMBL
LigandPNGBDBM50138154(Biphenyl-4-carboxylic acid {1-[(5-aminomethyl-2-me...)
Affinity DataIC50: 450nMAssay Description:Compound was tested for inhibition of human activated protein C (APC)More data for this Ligand-Target Pair
In Depth
Date in BDB:
11/10/2009
Entry Details Article
PubMed
TargetPlasminogen(Human)
The Bristol-Myers Squibb Pharmaceutical Research Institute

Curated by ChEMBL
LigandPNGBDBM50138154(Biphenyl-4-carboxylic acid {1-[(5-aminomethyl-2-me...)
Affinity DataIC50: 450nMAssay Description:Compound was tested for inhibition of human plasminMore data for this Ligand-Target Pair
In Depth
Date in BDB:
11/10/2009
Entry Details Article
PubMed
TargetSerine protease 1(Human)
The Bristol-Myers Squibb Pharmaceutical Research Institute

Curated by ChEMBL
LigandPNGBDBM50138154(Biphenyl-4-carboxylic acid {1-[(5-aminomethyl-2-me...)
Affinity DataIC50: 450nMAssay Description:Compound was tested for inhibition of human trypsinMore data for this Ligand-Target Pair
In Depth
Date in BDB:
11/10/2009
Entry Details Article
PubMed
TargetTryptase beta-2/delta/gamma(Human)
The Bristol-Myers Squibb Pharmaceutical Research Institute

Curated by ChEMBL
LigandPNGBDBM50138154(Biphenyl-4-carboxylic acid {1-[(5-aminomethyl-2-me...)
Affinity DataIC50: 74nMAssay Description:Inhibition of human tryptase.More data for this Ligand-Target Pair
In Depth
Date in BDB:
11/10/2009
Entry Details Article
PubMed