BDBM50138002 3-Hydroxy-10-keto-N-(3,3-dimethylallyl)morphinan::CHEMBL295402

SMILES [#6]\[#6](-[#6])=[#6]\[#6]-[#7]-1-[#6]-[#6][C@]23[#6]-[#6]-[#6]-[#6]-[#6@H]2-[#6@H]-1-[#6](=O)-c1ccc(-[#8])cc31

InChI Key InChIKey=MDCJEOOPLAKPGM-UHFFFAOYSA-N

Data  3 KI

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
Find this compound or compounds like it in BindingDB:
   Substructure
Similarity at least:  must be >=0.5
Exact match

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 3 hits for monomerid = 50138002   

TargetKappa-type opioid receptor(Guinea pig)
Harvard Medical School

Curated by ChEMBL
LigandPNGBDBM50138002(3-Hydroxy-10-keto-N-(3,3-dimethylallyl)morphinan |...)
Affinity DataKi:  7.40nMAssay Description:Binding affinity against opioid receptor kappa 1 using [3H]-U-69,593 as radioligand in guinea pig brain membranes.More data for this Ligand-Target Pair
In Depth
Date in BDB:
11/10/2009
Entry Details Article
PubMed
TargetMu-type opioid receptor(Guinea pig)
Harvard Medical School

Curated by ChEMBL
LigandPNGBDBM50138002(3-Hydroxy-10-keto-N-(3,3-dimethylallyl)morphinan |...)
Affinity DataKi:  19nMAssay Description:Binding affinity against opioid receptor mu 1 using [3H]DAMGO as radioligand in guinea pig brain membranes.More data for this Ligand-Target Pair
In Depth
Date in BDB:
11/10/2009
Entry Details Article
PubMed
TargetDelta-type opioid receptor(Human)
Harvard Medical School

Curated by ChEMBL
LigandPNGBDBM50138002(3-Hydroxy-10-keto-N-(3,3-dimethylallyl)morphinan |...)
Affinity DataKi:  1.10E+3nMAssay Description:Binding affinity against opioid receptor delta 1 using [3H]naltrindole as radioligand in guinea pig brain membranes.More data for this Ligand-Target Pair
In Depth
Date in BDB:
11/10/2009
Entry Details Article
PubMed