BDBM50138001 3-Cyano-N-cyclobutylmethylmorphinan::CHEMBL48157

SMILES N#Cc1ccc2C[C@@H]3[C@@H]4CCCC[C@]4(CCN3CC3CCC3)c2c1

InChI Key InChIKey=SRPOCVPRBWPZFP-UHFFFAOYSA-N

Data  3 KI

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
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Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 3 hits for monomerid = 50138001   

TargetKappa-type opioid receptor(Guinea pig)
Harvard Medical School

Curated by ChEMBL
LigandPNGBDBM50138001(3-Cyano-N-cyclobutylmethylmorphinan | CHEMBL48157)
Affinity DataKi:  6nMAssay Description:Binding affinity against opioid receptor kappa 1 using [3H]-U-69,593 as radioligand in guinea pig brain membranes.More data for this Ligand-Target Pair
In Depth
Date in BDB:
11/10/2009
Entry Details Article
PubMed
TargetMu-type opioid receptor(Guinea pig)
Harvard Medical School

Curated by ChEMBL
LigandPNGBDBM50138001(3-Cyano-N-cyclobutylmethylmorphinan | CHEMBL48157)
Affinity DataKi:  37nMAssay Description:Binding affinity against opioid receptor mu 1 using [3H]DAMGO as radioligand in guinea pig brain membranes.More data for this Ligand-Target Pair
In Depth
Date in BDB:
11/10/2009
Entry Details Article
PubMed
TargetDelta-type opioid receptor(Human)
Harvard Medical School

Curated by ChEMBL
LigandPNGBDBM50138001(3-Cyano-N-cyclobutylmethylmorphinan | CHEMBL48157)
Affinity DataKi:  1.90E+3nMAssay Description:Binding affinity against opioid receptor delta 1 using [3H]naltrindole as radioligand in guinea pig brain membranes.More data for this Ligand-Target Pair
In Depth
Date in BDB:
11/10/2009
Entry Details Article
PubMed