BDBM50137989 3-Hydroxy-10-keto-N-(tetrahydrofuran-2-yl)methylmorphinan::CHEMBL301804

SMILES Oc1ccc2C(=O)[C@@H]3[C@@H]4CCCC[C@]4(CCN3C[C@@H]3CCCO3)c2c1

InChI Key InChIKey=BSCRKXLANCGZGY-UHFFFAOYSA-N

Data  3 KI

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
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Similarity at least:  must be >=0.5
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Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 3 hits for monomerid = 50137989   

TargetKappa-type opioid receptor(Guinea pig)
Harvard Medical School

Curated by ChEMBL
LigandPNGBDBM50137989(3-Hydroxy-10-keto-N-(tetrahydrofuran-2-yl)methylmo...)
Affinity DataKi:  0.180nMAssay Description:Binding affinity against opioid receptor kappa 1 using [3H]-U-69,593 as radioligand in guinea pig brain membranes.More data for this Ligand-Target Pair
In Depth
Date in BDB:
11/10/2009
Entry Details Article
PubMed
TargetMu-type opioid receptor(Guinea pig)
Harvard Medical School

Curated by ChEMBL
LigandPNGBDBM50137989(3-Hydroxy-10-keto-N-(tetrahydrofuran-2-yl)methylmo...)
Affinity DataKi:  0.380nMAssay Description:Binding affinity against opioid receptor mu 1 using [3H]DAMGO as radioligand in guinea pig brain membranes.More data for this Ligand-Target Pair
In Depth
Date in BDB:
11/10/2009
Entry Details Article
PubMed
TargetDelta-type opioid receptor(Human)
Harvard Medical School

Curated by ChEMBL
LigandPNGBDBM50137989(3-Hydroxy-10-keto-N-(tetrahydrofuran-2-yl)methylmo...)
Affinity DataKi:  1nMAssay Description:Binding affinity against opioid receptor delta 1 using [3H]naltrindole as radioligand in guinea pig brain membranes.More data for this Ligand-Target Pair
In Depth
Date in BDB:
11/10/2009
Entry Details Article
PubMed