BDBM50137986 3-Hydroxy-10-keto-N-(3-fluoropropyl)morphinan::CHEMBL295237

SMILES Oc1ccc2C(=O)[C@@H]3[C@@H]4CCCC[C@]4(CCN3CCCF)c2c1

InChI Key InChIKey=LDUCOIQQNZJWTI-UHFFFAOYSA-N

Data  3 KI

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
Find this compound or compounds like it in BindingDB:
   Substructure
Similarity at least:  must be >=0.5
Exact match

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 3 hits for monomerid = 50137986   

TargetKappa-type opioid receptor(Guinea pig)
Harvard Medical School

Curated by ChEMBL
LigandPNGBDBM50137986(3-Hydroxy-10-keto-N-(3-fluoropropyl)morphinan | CH...)
Affinity DataKi:  2.5nMAssay Description:Binding affinity against opioid receptor kappa 1 using [3H]-U-69,593 as radioligand in guinea pig brain membranes.More data for this Ligand-Target Pair
In Depth
Date in BDB:
11/10/2009
Entry Details Article
PubMed
TargetMu-type opioid receptor(Guinea pig)
Harvard Medical School

Curated by ChEMBL
LigandPNGBDBM50137986(3-Hydroxy-10-keto-N-(3-fluoropropyl)morphinan | CH...)
Affinity DataKi:  20nMAssay Description:Binding affinity against opioid receptor mu 1 using [3H]DAMGO as radioligand in guinea pig brain membranes.More data for this Ligand-Target Pair
In Depth
Date in BDB:
11/10/2009
Entry Details Article
PubMed
TargetDelta-type opioid receptor(Human)
Harvard Medical School

Curated by ChEMBL
LigandPNGBDBM50137986(3-Hydroxy-10-keto-N-(3-fluoropropyl)morphinan | CH...)
Affinity DataKi:  690nMAssay Description:Binding affinity against opioid receptor delta 1 using [3H]naltrindole as radioligand in guinea pig brain membranes.More data for this Ligand-Target Pair
In Depth
Date in BDB:
11/10/2009
Entry Details Article
PubMed