BDBM50137912 (Biphenyl-4-sulfinyl)-acetic acid::(Biphenyl-4-sulfonyl)-acetic acid::2-(biphenyl-4-ylsulfonyl)acetic acid::CHEMBL178590

SMILES OC(=O)CS(=O)(=O)c1ccc(cc1)-c1ccccc1

InChI Key InChIKey=LXRDFDDOMVFUNV-UHFFFAOYSA-N

Data  1 KI  9 IC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
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Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 10 hits for monomerid = 50137912   

TargetReplication protein E1(Human papillomavirus type 11)
Boehringer Ingelheim (Canada)

Curated by ChEMBL
LigandPNGBDBM50137912((Biphenyl-4-sulfinyl)-acetic acid | (Biphenyl-4-su...)
Affinity DataIC50: 2.00E+3nMAssay Description:Ability to inhibit in vitro ATPase activity of human papillomavirus (HPV6) E1 helicaseMore data for this Ligand-Target Pair
In Depth
Date in BDB:
11/10/2009
Entry Details Article
PubMed
TargetDNA primase(HHV-1)
Boehringer Ingelheim (Canada)

Curated by ChEMBL
LigandPNGBDBM50137912((Biphenyl-4-sulfinyl)-acetic acid | (Biphenyl-4-su...)
Affinity DataIC50: 8.00E+4nMAssay Description:Inhibitory concentration against herpes simplex virus helicase primase 8 (HSV)More data for this Ligand-Target Pair
In Depth
Date in BDB:
11/10/2009
Entry Details Article
PubMed
TargetInterstitial collagenase(Human)
Jadavpur University

Curated by ChEMBL
LigandPNGBDBM50137912((Biphenyl-4-sulfinyl)-acetic acid | (Biphenyl-4-su...)
Affinity DataIC50: 3.80E+5nMAssay Description:Inhibition of MMP-1 (unknown origin)More data for this Ligand-Target Pair
In Depth
Date in BDB:
6/20/2023
Entry Details
PubMed
Target72 kDa type IV collagenase(Human)
Jadavpur University

Curated by ChEMBL
LigandPNGBDBM50137912((Biphenyl-4-sulfinyl)-acetic acid | (Biphenyl-4-su...)
Affinity DataIC50: 1.25E+4nMAssay Description:Inhibition of MMP-2 (unknown origin)More data for this Ligand-Target Pair
In Depth
Date in BDB:
6/20/2023
Entry Details
PubMed
TargetStromelysin-1(Human)
Jadavpur University

Curated by ChEMBL
LigandPNGBDBM50137912((Biphenyl-4-sulfinyl)-acetic acid | (Biphenyl-4-su...)
Affinity DataIC50: 3.64E+5nMAssay Description:Inhibition of MMP-3 (unknown origin)More data for this Ligand-Target Pair
In Depth
Date in BDB:
6/20/2023
Entry Details
PubMed
TargetMatrilysin(Human)
Jadavpur University

Curated by ChEMBL
LigandPNGBDBM50137912((Biphenyl-4-sulfinyl)-acetic acid | (Biphenyl-4-su...)
Affinity DataIC50: 1.42E+4nMAssay Description:Inhibition of MMP-7 (unknown origin)More data for this Ligand-Target Pair
In Depth
Date in BDB:
6/20/2023
Entry Details
PubMed
TargetMatrix metalloproteinase-9(Human)
Jadavpur University

Curated by ChEMBL
LigandPNGBDBM50137912((Biphenyl-4-sulfinyl)-acetic acid | (Biphenyl-4-su...)
Affinity DataIC50: 2.12E+5nMAssay Description:Inhibition of MMP-9 (unknown origin)More data for this Ligand-Target Pair
In Depth
Date in BDB:
6/20/2023
Entry Details
PubMed
TargetCollagenase 3(Human)
Jadavpur University

Curated by ChEMBL
LigandPNGBDBM50137912((Biphenyl-4-sulfinyl)-acetic acid | (Biphenyl-4-su...)
Affinity DataIC50: 1.01E+5nMAssay Description:Inhibition of MMP-13 (unknown origin)More data for this Ligand-Target Pair
In Depth
Date in BDB:
6/20/2023
Entry Details
PubMed
TargetMatrix metalloproteinase-14(Human)
Jadavpur University

Curated by ChEMBL
LigandPNGBDBM50137912((Biphenyl-4-sulfinyl)-acetic acid | (Biphenyl-4-su...)
Affinity DataIC50: 165nMAssay Description:Inhibition of MMP-14 (unknown origin)More data for this Ligand-Target Pair
In Depth
Date in BDB:
6/20/2023
Entry Details
PubMed
TargetReplication protein E1(Human papillomavirus type 11)
Boehringer Ingelheim (Canada)

Curated by ChEMBL
LigandPNGBDBM50137912((Biphenyl-4-sulfinyl)-acetic acid | (Biphenyl-4-su...)
Affinity DataKi:  2.00E+3nMAssay Description:Binding affinity for human papillomavirus (HPV6) E1 helicaseMore data for this Ligand-Target Pair
In Depth
Date in BDB:
11/10/2009
Entry Details Article
PubMed