BDBM50137696 (S)-4-(S)-Hydroxy-5-[(S)-2-((S)-2-hydroxy-4-methyl-pentanoylamino)-propionylamino]-2-methyl-6-phenyl-hexanoic acid {(S)-2-methyl-1-[(pyridin-4-ylmethyl)-carbamoyl]-propyl}-amide::CHEMBL82102

SMILES CC(C)C[C@H](O)C(=O)N[C@@H](C)C(=O)N[C@@H](Cc1ccccc1)[C@@H](O)C[C@@H](C)C(=O)N[C@@H](C(C)C)C(=O)NCc1ccncc1

InChI Key InChIKey=IWTIFQDWLDJQRW-UHFFFAOYSA-N

Data  1 IC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
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Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 1 hit for monomerid = 50137696   

TargetBeta-secretase 1(Human)
Eli Lilly

Curated by ChEMBL
LigandPNGBDBM50137696((S)-4-(S)-Hydroxy-5-[(S)-2-((S)-2-hydroxy-4-methyl...)
Affinity DataIC50: 230nMAssay Description:In vitro inhibitory activity against Beta-secretase 1 in human HEK293 cellsMore data for this Ligand-Target Pair
In Depth
Date in BDB:
10/10/2012
Entry Details Article
PubMed