BDBM50137677 4-(3,4,5-Trihydroxy-6-hydroxymethyl-tetrahydro-pyran-2-ylamino)-benzenesulfonamide::CHEMBL72447::N-(p-sulfamoylphenyl)-alpha-glycopyranosylamine, 1::N-(p-sulfamoylphenyl)-alpha-glycopyranosylamine, 2::N-(p-sulfamoylphenyl)-alpha-glycopyranosylamine, 3

SMILES c1cc(ccc1N[C@H]2[C@@H]([C@H]([C@@H]([C@H](O2)CO)O)O)O)S(=O)(=O)N

InChI Key InChIKey=RMCYKIOWPVOBJX-UHFFFAOYSA-N

Data  9 KI

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
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Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 9 hits for monomerid = 50137677   

TargetCarbonic anhydrase 6(Human)
Institut Des BiomolÉCules Max Mousseron (Ibmm)

LigandPNGBDBM50137677(N-(p-sulfamoylphenyl)-alpha-glycopyranosylamine, 2...)
Affinity DataKi:  0.640nM ΔG°:  -12.3kcal/molepH: 7.5 T: 2°CAssay Description:Inhibition assay using carbonic anhydrases with an SX.18MV-R, a stopped-flow instrument from Applied Photophysics was used for assaying the CA cataly...More data for this Ligand-Target Pair
In Depth
Date in BDB:
11/28/2011
Entry Details Article
PubMed
TargetCarbonic anhydrase 6(Human)
Institut Des BiomolÉCules Max Mousseron (Ibmm)

LigandPNGBDBM50137677(N-(p-sulfamoylphenyl)-alpha-glycopyranosylamine, 2...)
Affinity DataKi:  10.1nM ΔG°:  -10.7kcal/molepH: 7.5 T: 2°CAssay Description:Inhibition assay using carbonic anhydrases with an SX.18MV-R, a stopped-flow instrument from Applied Photophysics was used for assaying the CA cataly...More data for this Ligand-Target Pair
In Depth
Date in BDB:
11/28/2011
Entry Details Article
PubMed
TargetCarbonic anhydrase 2(Human)
Institut Des BiomolÉCules Max Mousseron (Ibmm)

LigandPNGBDBM50137677(N-(p-sulfamoylphenyl)-alpha-glycopyranosylamine, 2...)
Affinity DataKi:  18nM ΔG°:  -10.4kcal/molepH: 7.5 T: 2°CAssay Description:Inhibition assay using carbonic anhydrases with an SX.18MV-R, a stopped-flow instrument from Applied Photophysics was used for assaying the CA cataly...More data for this Ligand-Target Pair
In Depth
Date in BDB:
11/28/2011
Entry Details Article
PubMed
TargetCarbonic anhydrase 2(Human)
Institut Des BiomolÉCules Max Mousseron (Ibmm)

LigandPNGBDBM50137677(N-(p-sulfamoylphenyl)-alpha-glycopyranosylamine, 2...)
Affinity DataKi:  23nM ΔG°:  -10.2kcal/molepH: 7.5 T: 2°CAssay Description:Inhibition assay using carbonic anhydrases with an SX.18MV-R, a stopped-flow instrument from Applied Photophysics was used for assaying the CA cataly...More data for this Ligand-Target Pair
In Depth
Date in BDB:
11/28/2011
Entry Details Article
PubMed
TargetCarbonic anhydrase 2(Human)
Institut Des BiomolÉCules Max Mousseron (Ibmm)

LigandPNGBDBM50137677(N-(p-sulfamoylphenyl)-alpha-glycopyranosylamine, 2...)
Affinity DataKi:  25nM ΔG°:  -10.2kcal/molepH: 7.5 T: 2°CAssay Description:Inhibition assay using carbonic anhydrases with an SX.18MV-R, a stopped-flow instrument from Applied Photophysics was used for assaying the CA cataly...More data for this Ligand-Target Pair
In Depth
Date in BDB:
11/28/2011
Entry Details Article
PubMed
TargetCarbonic anhydrase 6(Human)
Institut Des BiomolÉCules Max Mousseron (Ibmm)

LigandPNGBDBM50137677(N-(p-sulfamoylphenyl)-alpha-glycopyranosylamine, 2...)
Affinity DataKi:  34.1nM ΔG°:  -10.0kcal/molepH: 7.5 T: 2°CAssay Description:Inhibition assay using carbonic anhydrases with an SX.18MV-R, a stopped-flow instrument from Applied Photophysics was used for assaying the CA cataly...More data for this Ligand-Target Pair
In Depth
Date in BDB:
11/28/2011
Entry Details Article
PubMed
TargetCarbonic anhydrase 1(Human)
Institut Des BiomolÉCules Max Mousseron (Ibmm)

LigandPNGBDBM50137677(N-(p-sulfamoylphenyl)-alpha-glycopyranosylamine, 2...)
Affinity DataKi:  930nM ΔG°:  -8.08kcal/molepH: 7.5 T: 2°CAssay Description:Inhibition assay using carbonic anhydrases with an SX.18MV-R, a stopped-flow instrument from Applied Photophysics was used for assaying the CA cataly...More data for this Ligand-Target Pair
In Depth
Date in BDB:
11/28/2011
Entry Details Article
PubMed
TargetCarbonic anhydrase 1(Human)
Institut Des BiomolÉCules Max Mousseron (Ibmm)

LigandPNGBDBM50137677(N-(p-sulfamoylphenyl)-alpha-glycopyranosylamine, 2...)
Affinity DataKi:  1.00E+3nM ΔG°:  -8.04kcal/molepH: 7.5 T: 2°CAssay Description:Inhibition assay using carbonic anhydrases with an SX.18MV-R, a stopped-flow instrument from Applied Photophysics was used for assaying the CA cataly...More data for this Ligand-Target Pair
In Depth
Date in BDB:
11/28/2011
Entry Details Article
PubMed
TargetCarbonic anhydrase 1(Human)
Institut Des BiomolÉCules Max Mousseron (Ibmm)

LigandPNGBDBM50137677(N-(p-sulfamoylphenyl)-alpha-glycopyranosylamine, 2...)
Affinity DataKi:  1.20E+3nM ΔG°:  -7.94kcal/molepH: 7.5 T: 2°CAssay Description:Inhibition assay using carbonic anhydrases with an SX.18MV-R, a stopped-flow instrument from Applied Photophysics was used for assaying the CA cataly...More data for this Ligand-Target Pair
In Depth
Date in BDB:
11/28/2011
Entry Details Article
PubMed