BDBM50137616 4-Bromo-1-methoxy-naphthalene-2-carboxylic acid [2-(3,4-dihydro-1H-isoquinolin-2-yl)-ethyl]-amide::CHEMBL60133

SMILES COc1c(cc(Br)c2ccccc12)C(=O)NCCN1CCc2ccccc2C1

InChI Key InChIKey=LQOYFQQIZFEVDY-UHFFFAOYSA-N

Data  3 KI

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
Find this compound or compounds like it in BindingDB:
   Substructure
Similarity at least:  must be >=0.5
Exact match

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 3 hits for monomerid = 50137616   

TargetSigma non-opioid intracellular receptor 1(Human)
Wake Forest University School of Medicine

Curated by ChEMBL
LigandPNGBDBM50137616(4-Bromo-1-methoxy-naphthalene-2-carboxylic acid [2...)
Affinity DataKi:  15nMAssay Description:Inhibition of [3H](+)-pentazocine binding to Sigma opioid receptor of guiena pig brain membraneMore data for this Ligand-Target Pair
In Depth
Date in BDB:
11/10/2009
Entry Details Article
PubMed
TargetD(3) dopamine receptor(Rat)
Wake Forest University School of Medicine

Curated by ChEMBL
LigandPNGBDBM50137616(4-Bromo-1-methoxy-naphthalene-2-carboxylic acid [2...)
Affinity DataKi:  82nMAssay Description:Binding affinity at dopamine receptor D3 on Sf9 cells by [125I]IABN displacement.More data for this Ligand-Target Pair
In Depth
Date in BDB:
11/10/2009
Entry Details Article
PubMed
TargetD(2) dopamine receptor(Rat)
Wake Forest University School of Medicine

Curated by ChEMBL
LigandPNGBDBM50137616(4-Bromo-1-methoxy-naphthalene-2-carboxylic acid [2...)
Affinity DataKi:  132nMAssay Description:Binding affinity at dopamine receptor D2 on Sf9 cells by [125I]IABN displacement.More data for this Ligand-Target Pair
In Depth
Date in BDB:
11/10/2009
Entry Details Article
PubMed