BDBM50137479 1-Cyclohexyl-2-phenyl-1H-benzoimidazole-5-carboxylic acid::1-cyclohexyl-2-phenyl-1H-benzo[d]imidazole-5-carboxylic acid::CHEMBL361434

SMILES OC(=O)c1ccc2n(C3CCCCC3)c(nc2c1)-c1ccccc1

InChI Key InChIKey=DIHHAPXAXYGMEH-UHFFFAOYSA-N

Data  5 IC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
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Exact match

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 5 hits for monomerid = 50137479   

TargetRNA-directed RNA polymerase(Hepatitis C virus genotype 1b (isolate Con1) (HCV))
Boehringer Ingelheim (Canada)

Curated by ChEMBL
LigandPNGBDBM50137479(1-cyclohexyl-2-phenyl-1H-benzo[d]imidazole-5-carbo...)
Affinity DataIC50: 8.60E+3nMAssay Description:Inhibitory activity against NS5B polymerase of hepatitis C virusMore data for this Ligand-Target Pair
In Depth
Date in BDB:
11/10/2009
Entry Details Article
PubMed
TargetRNA-directed RNA polymerase(Hepatitis C virus genotype 1b (isolate Con1) (HCV))
Boehringer Ingelheim (Canada)

Curated by ChEMBL
LigandPNGBDBM50137479(1-cyclohexyl-2-phenyl-1H-benzo[d]imidazole-5-carbo...)
Affinity DataIC50: 6.50E+3nMAssay Description:Inhibition of HCV BK NS5B deltaC55 RNA dependent RNA polymeraseMore data for this Ligand-Target Pair
In Depth
Date in BDB:
11/10/2009
Entry Details Article
PubMed
TargetGenome polyprotein(Poliovirus type 1 (strain Mahoney))
Boehringer Ingelheim (Canada)

Curated by ChEMBL
LigandPNGBDBM50137479(1-cyclohexyl-2-phenyl-1H-benzo[d]imidazole-5-carbo...)
Affinity DataIC50: 2.50E+5nMAssay Description:Inhibitory activity against polio virus RNA polymeraseMore data for this Ligand-Target Pair
In Depth
Date in BDB:
11/10/2009
Entry Details Article
PubMed
TargetRNA-directed RNA polymerase(Hepatitis C virus genotype 1b (isolate Con1) (HCV))
Boehringer Ingelheim (Canada)

Curated by ChEMBL
LigandPNGBDBM50137479(1-cyclohexyl-2-phenyl-1H-benzo[d]imidazole-5-carbo...)
Affinity DataIC50: 3.10E+3nMAssay Description:Inhibition of HCV 1b NS5B delta21 RNA dependent RNA polymerase by SPAMore data for this Ligand-Target Pair
In Depth
Date in BDB:
12/8/2012
Entry Details Article
PubMed
TargetDNA-directed RNA polymerase subunit beta(Escherichia coli (strain K12))
Boehringer Ingelheim (Canada)

Curated by ChEMBL
LigandPNGBDBM50137479(1-cyclohexyl-2-phenyl-1H-benzo[d]imidazole-5-carbo...)
Affinity DataIC50: 5.00E+5nMAssay Description:Inhibitory activity against calf thymus RNA polymeraseMore data for this Ligand-Target Pair
In Depth
Date in BDB:
11/10/2009
Entry Details Article
PubMed