BDBM50137349 1-Cyano-4-ethoxy-2-oxo-2H-3-oxa-benzo[a]azulene-10-carboxylic acid ethyl ester::CHEMBL157082

SMILES CCOC(=O)c1c2cccccc2c2c(OCC)oc(=O)c(C#N)c12

InChI Key InChIKey=DFYSBOCNWBIFDR-UHFFFAOYSA-N

Data  1 IC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
Find this compound or compounds like it in BindingDB:
   Substructure
Similarity at least:  must be >=0.5
Exact match

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 1 hit for monomerid = 50137349   

TargetPolyunsaturated fatty acid lipoxygenase ALOX15(Human)
Tamkang University

Curated by ChEMBL
LigandPNGBDBM50137349(1-Cyano-4-ethoxy-2-oxo-2H-3-oxa-benzo[a]azulene-10...)
Affinity DataIC50: 2.42E+4nMAssay Description:Inhibitory activity against 15-lipoxygenase was determined obtained from soya beanMore data for this Ligand-Target Pair
In Depth
Date in BDB:
11/10/2009
Entry Details Article
PubMed