BDBM50137185 (1H-Indol-5-yl)-(6-phenyl-thieno[3,2-d]pyrimidin-4-yl)-amine::CHEMBL76432

SMILES N(c1ccc2[nH]ccc2c1)c1ncnc2cc(sc12)-c1ccccc1

InChI Key InChIKey=CGDLXUGHZUDIDJ-UHFFFAOYSA-N

Data  6 IC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
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   Substructure
Similarity at least:  must be >=0.5
Exact match

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 6 hits for monomerid = 50137185   

LigandPNGBDBM50137185((1H-Indol-5-yl)-(6-phenyl-thieno[3,2-d]pyrimidin-4...)
Affinity DataIC50: 48nMAssay Description:Inhibitory activity against Vascular endothelial growth factor receptorMore data for this Ligand-Target Pair
In Depth
Date in BDB:
11/10/2009
Entry Details Article
PubMed
TargetEpidermal growth factor receptor(Human)
Pfizer

Curated by ChEMBL
LigandPNGBDBM50137185((1H-Indol-5-yl)-(6-phenyl-thieno[3,2-d]pyrimidin-4...)
Affinity DataIC50: 68nMAssay Description:Inhibitory activity against epidermal growth factor receptorMore data for this Ligand-Target Pair
In Depth
Date in BDB:
11/10/2009
Entry Details Article
PubMed
TargetEpidermal growth factor receptor(Human)
Pfizer

Curated by ChEMBL
LigandPNGBDBM50137185((1H-Indol-5-yl)-(6-phenyl-thieno[3,2-d]pyrimidin-4...)
Affinity DataIC50: 68nMAssay Description:Inhibitory activity against epidermal growth factor receptorMore data for this Ligand-Target Pair
In Depth
Date in BDB:
11/10/2009
Entry Details Article
PubMed
LigandPNGBDBM50137185((1H-Indol-5-yl)-(6-phenyl-thieno[3,2-d]pyrimidin-4...)
Affinity DataIC50: 48nMAssay Description:Inhibitory activity against Vascular endothelial growth factor receptorMore data for this Ligand-Target Pair
In Depth
Date in BDB:
11/10/2009
Entry Details Article
PubMed
TargetEpidermal growth factor receptor(Human)
Pfizer

Curated by ChEMBL
LigandPNGBDBM50137185((1H-Indol-5-yl)-(6-phenyl-thieno[3,2-d]pyrimidin-4...)
Affinity DataIC50: 3nMAssay Description:Inhibition of EGFR (unknown origin)More data for this Ligand-Target Pair
In Depth
Date in BDB:
2/22/2021
Entry Details Article
PubMed
TargetVascular endothelial growth factor receptor 2(Human)
University of Ferrara

Curated by ChEMBL
LigandPNGBDBM50137185((1H-Indol-5-yl)-(6-phenyl-thieno[3,2-d]pyrimidin-4...)
Affinity DataIC50: 80nMAssay Description:Inhibition of VEGFR2 (unknown origin)More data for this Ligand-Target Pair
In Depth
Date in BDB:
2/22/2021
Entry Details Article
PubMed