BDBM50136890 CHEMBL152208::[2-Chloro-4-(4-fluoro-2-methyl-phenylamino)-phenyl]-o-tolyl-methanone

SMILES Cc1ccccc1C(=O)c1ccc(Nc2ccc(F)cc2C)cc1Cl

InChI Key InChIKey=QIBLVZMAUUVSMB-UHFFFAOYSA-N

Data  2 IC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
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Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 2 hits for monomerid = 50136890   

TargetMitogen-activated protein kinase 14(Human)
Leo Pharma

Curated by ChEMBL
LigandPNGBDBM50136890([2-Chloro-4-(4-fluoro-2-methyl-phenylamino)-phenyl...)
Affinity DataIC50: 4nMAssay Description:In vitro inhibitory activity determined against human mitogen-activated protein kinase p38 alphaMore data for this Ligand-Target Pair
In Depth
Date in BDB:
11/30/2012
Entry Details Article
PubMed
TargetMitogen-activated protein kinase 14(Human)
Leo Pharma

Curated by ChEMBL
LigandPNGBDBM50136890([2-Chloro-4-(4-fluoro-2-methyl-phenylamino)-phenyl...)
Affinity DataIC50: 4nMAssay Description:Inhibition of P38alphaMAPK (unknown origin)More data for this Ligand-Target Pair
In Depth
Date in BDB:
4/22/2024
Entry Details
PubMed