BDBM50136593 3-[(3R,4R)-1-(3-Chloro-benzyl)-3,4-dimethyl-piperidin-4-yl]-benzamide::CHEMBL138473

SMILES C[C@H]1CN(Cc2cccc(Cl)c2)CC[C@@]1(C)c1cccc(c1)C(N)=O

InChI Key InChIKey=CIWNAGFVIRHUEY-UHFFFAOYSA-N

Data  3 KI

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
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Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 3 hits for monomerid = 50136593   

TargetMu-type opioid receptor(Human)
Adolor

Curated by ChEMBL
LigandPNGBDBM50136593(3-[(3R,4R)-1-(3-Chloro-benzyl)-3,4-dimethyl-piperi...)
Affinity DataKi:  9.70nMAssay Description:Inhibition of binding of the non-selective opioid antagonist, [3H]diprenorphine, to cloned human mu opioid receptorMore data for this Ligand-Target Pair
In Depth
Date in BDB:
10/9/2012
Entry Details Article
PubMed
TargetDelta-type opioid receptor(Human)
Adolor

Curated by ChEMBL
LigandPNGBDBM50136593(3-[(3R,4R)-1-(3-Chloro-benzyl)-3,4-dimethyl-piperi...)
Affinity DataKi:  57nMAssay Description:Inhibition of [3H]diprenorphine binding to the cloned human delta opioid receptors using 10 uM concentration of the compoundMore data for this Ligand-Target Pair
In Depth
Date in BDB:
10/9/2012
Entry Details Article
PubMed
TargetKappa-type opioid receptor(Human)
Adolor

Curated by ChEMBL
LigandPNGBDBM50136593(3-[(3R,4R)-1-(3-Chloro-benzyl)-3,4-dimethyl-piperi...)
Affinity DataKi:  190nMAssay Description:Binding affinity at cloned human kappa opioid receptor by [3H]diprenorphine displacement.More data for this Ligand-Target Pair
In Depth
Date in BDB:
10/9/2012
Entry Details Article
PubMed