BDBM50136553 CHEMBL3753479

SMILES CC(C)Cc1cc(nc(C)n1)-c1nc(no1)-c1ccc(O[C@@H]2CCC(=O)NC2)c(F)c1

InChI Key InChIKey=GMEODUAZQQLOFF-UHFFFAOYSA-N

Data  3 EC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
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Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 3 hits for monomerid = 50136553   

TargetSphingosine 1-phosphate receptor 1(Human)
Boehringer Ingelheim Pharmaceuticals

Curated by ChEMBL
LigandPNGBDBM50136553(CHEMBL3753479)
Affinity DataEC50:  50nMAssay Description:Agonist activity at human S1P1 receptor expressed in EDG1-bla U2OS cells incubated for 18 hrs prior to GenBlazer substrate addition by beta-arrestin ...More data for this Ligand-Target Pair
In Depth
Date in BDB:
5/28/2017
Entry Details Article
PubMed
TargetSphingosine 1-phosphate receptor 3(Human)
Boehringer Ingelheim Pharmaceuticals

Curated by ChEMBL
LigandPNGBDBM50136553(CHEMBL3753479)
Affinity DataEC50: >1.00E+4nMAssay Description:Agonist activity at human S1P3 receptor expressed in EDG3-bla U2OS cells incubated for 18 hrs prior to GenBlazer substrate addition by beta-arrestin ...More data for this Ligand-Target Pair
In Depth
Date in BDB:
5/28/2017
Entry Details Article
PubMed
TargetSphingosine 1-phosphate receptor 5(Human)
Boehringer Ingelheim Pharmaceuticals

Curated by ChEMBL
LigandPNGBDBM50136553(CHEMBL3753479)
Affinity DataEC50:  360nMAssay Description:Agonist activity at human S1P5 receptor expressed in EDG8-bla U2OS cells incubated for 18 hrs prior to GenBlazer substrate addition by beta-arrestin ...More data for this Ligand-Target Pair
In Depth
Date in BDB:
5/28/2017
Entry Details Article
PubMed