BDBM50136450 7-Chloro-1H-indole-2-carboxylic acid (1-methyl-2-oxo-1,2,3,4-tetrahydro-quinolin-3-yl)-amide::CHEMBL136168

SMILES CN1C(=O)C(Cc2ccccc12)NC(=O)c1cc2cccc(Cl)c2[nH]1

InChI Key InChIKey=FPTUMUAOXPDCRC-UHFFFAOYSA-N

Data  3 IC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
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Similarity at least:  must be >=0.5
Exact match

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 3 hits for monomerid = 50136450   

TargetGlycogen phosphorylase, muscle form(Human)
Merck Research Laboratories

Curated by ChEMBL
LigandPNGBDBM50136450(7-Chloro-1H-indole-2-carboxylic acid (1-methyl-2-o...)
Affinity DataIC50: 88nMAssay Description:Inhibitory concentration against recombinant human muscle glycogen phosphorylase a (HMGPa)More data for this Ligand-Target Pair
In Depth
Date in BDB:
11/10/2009
Entry Details Article
PubMed
TargetGlycogen phosphorylase, liver form(Human)
Merck Research Laboratories

Curated by ChEMBL
LigandPNGBDBM50136450(7-Chloro-1H-indole-2-carboxylic acid (1-methyl-2-o...)
Affinity DataIC50: 88nMAssay Description:Inhibitory concentration against recombinant human liver glycogen phosphorylase a (HLGPa)More data for this Ligand-Target Pair
In Depth
Date in BDB:
11/10/2009
Entry Details Article
PubMed
TargetGlycogen phosphorylase, liver form(Human)
Merck Research Laboratories

Curated by ChEMBL
LigandPNGBDBM50136450(7-Chloro-1H-indole-2-carboxylic acid (1-methyl-2-o...)
Affinity DataIC50: 88nMAssay Description:Inhibition of human liver glycogen phosphorylase 1a assessed as release of phosphate from glucose-1- phosphate after 20 minsMore data for this Ligand-Target Pair
In Depth
Date in BDB:
3/23/2012
Entry Details Article
PubMed