BDBM50136387 C-(4-Chloro-phenyl)-C-[5-(3-chloro-phenyl)-imidazo[1,2-a]quinolin-7-yl]-C-(3-methyl-3H-imidazol-4-yl)-methylamine::CHEMBL335609

SMILES Cn1cncc1C(N)(c1ccc(Cl)cc1)c1ccc2c(c1)c(cc1nccn21)-c1cccc(Cl)c1

InChI Key InChIKey=CGJFRYFIVOQHJK-UHFFFAOYSA-N

Data  1 IC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
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Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 1 hit for monomerid = 50136387   

TargetProtein farnesyltransferase subunit beta/geranylgeranyltransferase type-1 subunit alpha(Human)
Medicinal Chemistry Department Johnson & Johnson Pharmaceutical Research & Development (J&Jprd)

Curated by ChEMBL
LigandPNGBDBM50136387(C-(4-Chloro-phenyl)-C-[5-(3-chloro-phenyl)-imidazo...)
Affinity DataIC50: 7nMAssay Description:Inhibition of [3H]FPP incorporation into biotinylated laminB peptide by farnesyl transferaseMore data for this Ligand-Target Pair
In Depth
Date in BDB:
11/10/2009
Entry Details Article
PubMed