BDBM50136248 (1S,2S)-Cyclohexane-1,2-dicarboxylic acid 1-hydroxyamide 2-{[4-(quinolin-5-yloxymethyl)-phenyl]-amide}::CHEMBL341702

SMILES ONC(=O)[C@H]1CCCC[C@@H]1C(=O)Nc1ccc(COc2cccc3ncccc23)cc1

InChI Key InChIKey=JKNLEZFIFUXSHW-UHFFFAOYSA-N

Data  1 KI  1 IC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
Find this compound or compounds like it in BindingDB:
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Similarity at least:  must be >=0.5
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Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 2 hits for monomerid = 50136248   

TargetDisintegrin and metalloproteinase domain-containing protein 17(Pig)
Bristol-Myers Squibb Pharmaceutical Research Institute

Curated by ChEMBL
LigandPNGBDBM50136248((1S,2S)-Cyclohexane-1,2-dicarboxylic acid 1-hydrox...)
Affinity DataIC50: 45nMAssay Description:Inhibition of porcine TACEMore data for this Ligand-Target Pair
In Depth
Date in BDB:
11/10/2009
Entry Details Article
PubMed
TargetInterstitial collagenase(Human)
Bristol-Myers Squibb Pharmaceutical Research Institute

Curated by ChEMBL
LigandPNGBDBM50136248((1S,2S)-Cyclohexane-1,2-dicarboxylic acid 1-hydrox...)
Affinity DataKi: >4.95E+3nMAssay Description:Inhibition of matrix metalloprotease-1 (MMP-1)More data for this Ligand-Target Pair
In Depth
Date in BDB:
11/10/2009
Entry Details Article
PubMed