BDBM50136145 4-[(4-Fluoro-phenyl)-(4-methoxy-phenoxy)-methyl]-piperidine::CHEMBL150442

SMILES COc1ccc(OC(C2CCNCC2)c2ccc(F)cc2)cc1

InChI Key InChIKey=YMZCCBPYNXMWGF-UHFFFAOYSA-N

Data  1 KI  2 IC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
Find this compound or compounds like it in BindingDB:
   Substructure
Similarity at least:  must be >=0.5
Exact match

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 3 hits for monomerid = 50136145   

Target5-hydroxytryptamine receptor 2A(Rat)
Faes Farma

Curated by ChEMBL
LigandPNGBDBM50136145(4-[(4-Fluoro-phenyl)-(4-methoxy-phenoxy)-methyl]-p...)
Affinity DataIC50: 1.00E+3nMAssay Description:Binding affinity against 5-hydroxytryptamine 2A receptor by displacement of [3H]-ketanserin from rat prefrontal cerebral cortex mambranesMore data for this Ligand-Target Pair
In Depth
Date in BDB:
11/30/2012
Entry Details Article
PubMed
Target5-hydroxytryptamine receptor 1A(Rat)
Faes Farma

Curated by ChEMBL
LigandPNGBDBM50136145(4-[(4-Fluoro-phenyl)-(4-methoxy-phenoxy)-methyl]-p...)
Affinity DataIC50: 1.00E+3nMAssay Description:Binding affinity against 5-hydroxytryptamine 1A receptor (5-HT1A) by displacement of [3H]8-OH-DPAT from rat hippocampus membranesMore data for this Ligand-Target Pair
In Depth
Date in BDB:
11/30/2012
Entry Details Article
PubMed
TargetSodium-dependent serotonin transporter(Rat)
Faes Farma

Curated by ChEMBL
LigandPNGBDBM50136145(4-[(4-Fluoro-phenyl)-(4-methoxy-phenoxy)-methyl]-p...)
Affinity DataKi:  0.900nMAssay Description:Binding affinity to the serotonin transporter (SERT) measured by displacement of [3H]paroxetine in male wistar ratsMore data for this Ligand-Target Pair
In Depth
Date in BDB:
11/30/2012
Entry Details Article
PubMed