BDBM50136133 4-[(3-Chloro-phenoxy)-phenyl-methyl]-piperidine::CHEMBL356400

SMILES Clc1cccc(OC(C2CCNCC2)c2ccccc2)c1

InChI Key InChIKey=XWKDJWUGOIMATK-UHFFFAOYSA-N

Data  5 KI  8 IC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
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Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 13 hits for monomerid = 50136133   

Target5-hydroxytryptamine receptor 1A(Rat)
Faes Farma

Curated by ChEMBL
LigandPNGBDBM50136133(4-[(3-Chloro-phenoxy)-phenyl-methyl]-piperidine | ...)
Affinity DataIC50: 1.00E+3nMAssay Description:Binding affinity against 5-hydroxytryptamine 1A receptor (5-HT1A) by displacement of [3H]8-OH-DPAT from rat hippocampus membranesMore data for this Ligand-Target Pair
In Depth
Date in BDB:
11/30/2012
Entry Details Article
PubMed
TargetSodium-dependent dopamine transporter(Rat)
Faes Farma

Curated by ChEMBL
LigandPNGBDBM50136133(4-[(3-Chloro-phenoxy)-phenyl-methyl]-piperidine | ...)
Affinity DataIC50: 500nMAssay Description:Binding affinity against dopamine transporter (DAT) by displacement of [3H]WIN-35428 in male wistar ratsMore data for this Ligand-Target Pair
In Depth
Date in BDB:
11/30/2012
Entry Details Article
PubMed
Target5-hydroxytryptamine receptor 2A(Rat)
Faes Farma

Curated by ChEMBL
LigandPNGBDBM50136133(4-[(3-Chloro-phenoxy)-phenyl-methyl]-piperidine | ...)
Affinity DataIC50: 1.00E+3nMAssay Description:Binding affinity against 5-hydroxytryptamine 2A receptor by displacement of [3H]-ketanserin from rat prefrontal cerebral cortex mambranesMore data for this Ligand-Target Pair
In Depth
Date in BDB:
11/30/2012
Entry Details Article
PubMed
Target5-hydroxytryptamine receptor 2A(Rat)
Faes Farma

Curated by ChEMBL
LigandPNGBDBM50136133(4-[(3-Chloro-phenoxy)-phenyl-methyl]-piperidine | ...)
Affinity DataIC50: 1.00E+3nMAssay Description:Binding affinity against 5-hydroxytryptamine 2A receptor by displacement of [3H]-ketanserin from rat prefrontal cerebral cortex mambranesMore data for this Ligand-Target Pair
In Depth
Date in BDB:
11/30/2012
Entry Details Article
PubMed
Target5-hydroxytryptamine receptor 2A(Rat)
Faes Farma

Curated by ChEMBL
LigandPNGBDBM50136133(4-[(3-Chloro-phenoxy)-phenyl-methyl]-piperidine | ...)
Affinity DataIC50: 1.00E+3nMAssay Description:Binding affinity against 5-hydroxytryptamine 2A receptor by displacement of [3H]-ketanserin from rat prefrontal cerebral cortex mambranesMore data for this Ligand-Target Pair
In Depth
Date in BDB:
11/30/2012
Entry Details Article
PubMed
Target5-hydroxytryptamine receptor 1A(Rat)
Faes Farma

Curated by ChEMBL
LigandPNGBDBM50136133(4-[(3-Chloro-phenoxy)-phenyl-methyl]-piperidine | ...)
Affinity DataIC50: 1.00E+3nMAssay Description:Binding affinity against 5-hydroxytryptamine 1A receptor (5-HT1A) by displacement of [3H]8-OH-DPAT from rat hippocampus membranesMore data for this Ligand-Target Pair
In Depth
Date in BDB:
11/30/2012
Entry Details Article
PubMed
Target5-hydroxytryptamine receptor 1A(Rat)
Faes Farma

Curated by ChEMBL
LigandPNGBDBM50136133(4-[(3-Chloro-phenoxy)-phenyl-methyl]-piperidine | ...)
Affinity DataIC50: 1.00E+3nMAssay Description:Binding affinity against 5-hydroxytryptamine 1A receptor (5-HT1A) by displacement of [3H]8-OH-DPAT from rat hippocampus membranesMore data for this Ligand-Target Pair
In Depth
Date in BDB:
11/30/2012
Entry Details Article
PubMed
TargetSodium-dependent dopamine transporter(Rat)
Faes Farma

Curated by ChEMBL
LigandPNGBDBM50136133(4-[(3-Chloro-phenoxy)-phenyl-methyl]-piperidine | ...)
Affinity DataIC50: 500nMAssay Description:Binding affinity against dopamine transporter (DAT) by displacement of [3H]WIN-35428 in male wistar ratsMore data for this Ligand-Target Pair
In Depth
Date in BDB:
11/30/2012
Entry Details Article
PubMed
TargetSodium-dependent serotonin transporter(Rat)
Faes Farma

Curated by ChEMBL
LigandPNGBDBM50136133(4-[(3-Chloro-phenoxy)-phenyl-methyl]-piperidine | ...)
Affinity DataKi:  2.60nMAssay Description:Binding affinity to the serotonin transporter (SERT) measured by displacement of [3H]paroxetine in male wistar ratsMore data for this Ligand-Target Pair
In Depth
Date in BDB:
11/30/2012
Entry Details Article
PubMed
TargetSodium-dependent serotonin transporter(Rat)
Faes Farma

Curated by ChEMBL
LigandPNGBDBM50136133(4-[(3-Chloro-phenoxy)-phenyl-methyl]-piperidine | ...)
Affinity DataKi:  3nMAssay Description:Binding affinity to the serotonin transporter (SERT) measured by displacement of [3H]paroxetine in male wistar ratsMore data for this Ligand-Target Pair
In Depth
Date in BDB:
11/30/2012
Entry Details Article
PubMed
TargetSodium-dependent serotonin transporter(Rat)
Faes Farma

Curated by ChEMBL
LigandPNGBDBM50136133(4-[(3-Chloro-phenoxy)-phenyl-methyl]-piperidine | ...)
Affinity DataKi:  3nMAssay Description:Binding affinity to the serotonin transporter (SERT) measured by displacement of [3H]paroxetine in male wistar ratsMore data for this Ligand-Target Pair
In Depth
Date in BDB:
11/30/2012
Entry Details Article
PubMed
TargetTransporter(Rat)
Faes Farma

Curated by ChEMBL
LigandPNGBDBM50136133(4-[(3-Chloro-phenoxy)-phenyl-methyl]-piperidine | ...)
Affinity DataKi:  55.8nMAssay Description:Binding affinity against norepinephrine transporter (NET) by displacement of [3H]nisoxetine in male wistar ratsMore data for this Ligand-Target Pair
In Depth
Date in BDB:
11/30/2012
Entry Details Article
PubMed
TargetTransporter(Rat)
Faes Farma

Curated by ChEMBL
LigandPNGBDBM50136133(4-[(3-Chloro-phenoxy)-phenyl-methyl]-piperidine | ...)
Affinity DataKi:  55.8nMAssay Description:Binding affinity against norepinephrine transporter (NET) by displacement of [3H]nisoxetine in male wistar ratsMore data for this Ligand-Target Pair
In Depth
Date in BDB:
11/30/2012
Entry Details Article
PubMed