BDBM50135932 (1S,3S)-3-Amino-4-difluoromethylene-cyclopentanecarboxylic acid::CHEMBL146927

SMILES [#7]-[#6@H]1-[#6]-[#6@H](-[#6]\[#6]-1=[#6](/F)F)-[#6](-[#8])=O

InChI Key InChIKey=MFSMFPSMHSFXFN-UHFFFAOYSA-N

Data  2 KI

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
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Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 2 hits for monomerid = 50135932   

Target4-aminobutyrate aminotransferase, mitochondrial(Pig)
Northwestern University

Curated by ChEMBL
LigandPNGBDBM50135932((1S,3S)-3-Amino-4-difluoromethylene-cyclopentaneca...)
Affinity DataKi:  3.10E+4nMAssay Description:Tested for inhibitory activity against gamma-aminobutyric acid aminotransferase from pig brainMore data for this Ligand-Target Pair
In Depth
Date in BDB:
11/10/2009
Entry Details Article
PubMed
Target4-aminobutyrate aminotransferase, mitochondrial(Pig)
Northwestern University

Curated by ChEMBL
LigandPNGBDBM50135932((1S,3S)-3-Amino-4-difluoromethylene-cyclopentaneca...)
Affinity DataKi:  5.90E+4nMAssay Description:Binding affinity pig brain GABA-AT assessed as inactivation constant using GABA as substrate in presence of NADP+ and alpha-ketoglutarate by SSDH cou...More data for this Ligand-Target Pair
In Depth
Date in BDB:
3/28/2022
Entry Details Article
PubMed