BDBM50135851 2,3,4,5-tetrabromo-6-(3,5-dibromo-2-hydroxy-phenoxy)-phenol::2,3,4,5-tetrabromo-6-(3,5-dibromo-2-hydroxyphenoxy)phenol::CHEMBL150098

SMILES Oc1c(Br)cc(Br)cc1Oc1c(O)c(Br)c(Br)c(Br)c1Br

InChI Key InChIKey=OMYZFHYKAPRFFQ-UHFFFAOYSA-N

Data  5 IC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
Find this compound or compounds like it in BindingDB:
   Substructure
Similarity at least:  must be >=0.5
Exact match

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 5 hits for monomerid = 50135851   

TargetAldo-keto reductase family 1 member B1(Human)
Instituto Biomar

Curated by ChEMBL
LigandPNGBDBM50135851(2,3,4,5-tetrabromo-6-(3,5-dibromo-2-hydroxyphenoxy...)
Affinity DataIC50: 6.40E+3nMAssay Description:In vitro inhibitory activity against recombinant human aldose reductase (ALR2) was determinedMore data for this Ligand-Target Pair
In Depth
Date in BDB:
11/10/2009
Entry Details Article
PubMed
TargetPolyunsaturated fatty acid lipoxygenase ALOX12(Human)
University of California

Curated by ChEMBL
LigandPNGBDBM50135851(2,3,4,5-tetrabromo-6-(3,5-dibromo-2-hydroxyphenoxy...)
Affinity DataIC50: 410nMAssay Description:Inhibitory effect on human platelet 12-lipoxygenaseMore data for this Ligand-Target Pair
In Depth
Date in BDB:
11/10/2009
Entry Details Article
PubMed
TargetPolyunsaturated fatty acid lipoxygenase ALOX15(Human)
University of California

Curated by ChEMBL
LigandPNGBDBM50135851(2,3,4,5-tetrabromo-6-(3,5-dibromo-2-hydroxyphenoxy...)
Affinity DataIC50: 790nMAssay Description:Inhibitory effect on human reticulocyte 15-lipoxygenaseMore data for this Ligand-Target Pair
In Depth
Date in BDB:
11/10/2009
Entry Details Article
PubMed
TargetPolyunsaturated fatty acid lipoxygenase ALOX15(Human)
University of California

Curated by ChEMBL
LigandPNGBDBM50135851(2,3,4,5-tetrabromo-6-(3,5-dibromo-2-hydroxyphenoxy...)
Affinity DataIC50: 1.30E+3nMAssay Description:Inhibition of 15-lipoxygenaseMore data for this Ligand-Target Pair
In Depth
Date in BDB:
8/25/2010
Entry Details Article
PubMed
TargetInduced myeloid leukemia cell differentiation protein Mcl-1(Human)
University of California

Curated by ChEMBL
LigandPNGBDBM50135851(2,3,4,5-tetrabromo-6-(3,5-dibromo-2-hydroxyphenoxy...)
Affinity DataIC50: 1.48E+4nMAssay Description:Inhibition of Bak binding to Mcl-1 by FRET assayMore data for this Ligand-Target Pair
In Depth
Date in BDB:
8/27/2020
Entry Details Article
PubMed