BDBM50135828 (2-Butyl-1-hydroxy-1-phosphono-octyl)-phosphonic acid::2-butyl-1-hydroxyl-octane-1,1-bisphosphonate::2-butyl-1-hydroxyoctane-1,1-diyldiphosphonic acid::CHEMBL54747

SMILES CCCCCCC(CCCC)C(O)(P(O)(O)=O)P(O)(O)=O

InChI Key InChIKey=WVPPATHVDSBURI-UHFFFAOYSA-N

Data  1 KI  3 IC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
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   Substructure
Similarity at least:  must be >=0.5
Exact match

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 4 hits for monomerid = 50135828   

TargetFarnesyl pyrophosphate synthase(Human)
University of Illinois At Urbana-Champaign

Curated by ChEMBL
LigandPNGBDBM50135828(2-butyl-1-hydroxyl-octane-1,1-bisphosphonate | 2-b...)
Affinity DataIC50: 6.80E+3nMAssay Description:Inhibitory activity against farnesyl Pyrophosphate Synthase was determinedMore data for this Ligand-Target Pair
In Depth
Date in BDB:
11/10/2009
Entry Details Article
PubMed
TargetPolyprenyl synthetase family protein(Leishmania donovani)
University of Illinois At Urbana-Champaign

Curated by ChEMBL
LigandPNGBDBM50135828(2-butyl-1-hydroxyl-octane-1,1-bisphosphonate | 2-b...)
Affinity DataIC50: 6.75E+3nMAssay Description:Inhibitory activity against Leishmania major Farnesyl diphosphate synthaseMore data for this Ligand-Target Pair
In Depth
Date in BDB:
11/10/2009
Entry Details Article
PubMed
TargetFarnesyl pyrophosphate synthase(Human)
University of Illinois At Urbana-Champaign

Curated by ChEMBL
LigandPNGBDBM50135828(2-butyl-1-hydroxyl-octane-1,1-bisphosphonate | 2-b...)
Affinity DataIC50: 6.76E+3nMAssay Description:Inhibitory activity against farnesyl Pyrophosphate Synthase expressed as #NAME (M)More data for this Ligand-Target Pair
In Depth
Date in BDB:
11/10/2009
Entry Details Article
PubMed
TargetFarnesyl pyrophosphate synthase(Human)
University of Illinois At Urbana-Champaign

Curated by ChEMBL
LigandPNGBDBM50135828(2-butyl-1-hydroxyl-octane-1,1-bisphosphonate | 2-b...)
Affinity DataKi:  650nMAssay Description:Binding affinity towards farnesyl Pyrophosphate Synthase using [14C]- isopentenyl pyrophosphate as radioligandMore data for this Ligand-Target Pair
In Depth
Date in BDB:
11/10/2009
Entry Details Article
PubMed