BDBM50135827 (Bis-phosphono-methyl)-propyl-ammonium::(phosphono-propylamino-methyl)-phosphonic acid::(propylamino)methylenediphosphonic acid::CHEMBL299717::propylaminomethylene-1,1-bisphosphonate

SMILES CCCN=C(P(O)(O)O)P(O)(O)=O

InChI Key InChIKey=ZMJYKHJPXIYKGB-UHFFFAOYSA-N

Data  1 KI  4 IC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
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Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 5 hits for monomerid = 50135827   

TargetFarnesyl pyrophosphate synthase(Human)
University of Illinois At Urbana-Champaign

Curated by ChEMBL
LigandPNGBDBM50135827(propylaminomethylene-1,1-bisphosphonate | (Bis-pho...)
Affinity DataIC50: 1.70E+3nMAssay Description:Inhibitory activity against farnesyl Pyrophosphate Synthase was determinedMore data for this Ligand-Target Pair
In Depth
Date in BDB:
11/10/2009
Entry Details Article
PubMed
TargetH(+)-exporting diphosphatase(Trypanosoma brucei)
University of Illinois At Urbana-Champaign

Curated by ChEMBL
LigandPNGBDBM50135827(propylaminomethylene-1,1-bisphosphonate | (Bis-pho...)
Affinity DataIC50: 4.77E+4nMAssay Description:Inhibition of recombinant Trypanosoma brucei soluble vacuolar pyrophosphatase expressed in Escherichia coliMore data for this Ligand-Target Pair
In Depth
Date in BDB:
12/4/2012
Entry Details Article
PubMed
TargetFarnesyl pyrophosphate synthase(Human)
University of Illinois At Urbana-Champaign

Curated by ChEMBL
LigandPNGBDBM50135827(propylaminomethylene-1,1-bisphosphonate | (Bis-pho...)
Affinity DataIC50: 1.66E+3nMAssay Description:Inhibitory activity against farnesyl Pyrophosphate Synthase expressed as #NAME (M)More data for this Ligand-Target Pair
In Depth
Date in BDB:
11/10/2009
Entry Details Article
PubMed
TargetPhosphotransferase(Trypanosoma cruzi)
University of Illinois At Urbana-Champaign

Curated by ChEMBL
LigandPNGBDBM50135827(propylaminomethylene-1,1-bisphosphonate | (Bis-pho...)
Affinity DataIC50: 3.00E+5nMAssay Description:Inhibitory activity against Trypanosoma cruzi hexokinaseMore data for this Ligand-Target Pair
In Depth
Date in BDB:
11/10/2009
Entry Details Article
PubMed
TargetFarnesyl pyrophosphate synthase(Human)
University of Illinois At Urbana-Champaign

Curated by ChEMBL
LigandPNGBDBM50135827(propylaminomethylene-1,1-bisphosphonate | (Bis-pho...)
Affinity DataKi:  160nMAssay Description:Binding affinity towards farnesyl Pyrophosphate Synthase using [14C]- isopentenyl pyrophosphate as radioligandMore data for this Ligand-Target Pair
In Depth
Date in BDB:
11/10/2009
Entry Details Article
PubMed