BDBM50135818 (pyridin-3-ylamino)methylenediphosphonic acid::3-[(Bis-phosphono-methyl)-amino]-pyridinium::CHEMBL301065::[(3-pyridinylamino)methylene]-1,1-bisphosphonate::[Phosphono-(pyridin-3-ylamino)-methyl]-phosphonic acid

SMILES OP(O)(=O)C(Nc1cccnc1)P(O)(O)=O

InChI Key InChIKey=IFOAJHQSAXHBDS-UHFFFAOYSA-N

Data  1 KI  3 IC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
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Similarity at least:  must be >=0.5
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Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 4 hits for monomerid = 50135818   

TargetFarnesyl pyrophosphate synthase(Human)
University of Illinois At Urbana-Champaign

Curated by ChEMBL
LigandPNGBDBM50135818([Phosphono-(pyridin-3-ylamino)-methyl]-phosphonic ...)
Affinity DataIC50: 160nMAssay Description:Inhibitory activity against farnesyl Pyrophosphate Synthase was determinedMore data for this Ligand-Target Pair
In Depth
Date in BDB:
11/10/2009
Entry Details Article
PubMed
TargetPolyprenyl synthetase family protein(Leishmania donovani)
University of Illinois At Urbana-Champaign

Curated by ChEMBL
LigandPNGBDBM50135818([Phosphono-(pyridin-3-ylamino)-methyl]-phosphonic ...)
Affinity DataIC50: 160nMAssay Description:Inhibitory activity against Leishmania major Farnesyl diphosphate synthaseMore data for this Ligand-Target Pair
In Depth
Date in BDB:
11/10/2009
Entry Details Article
PubMed
TargetFarnesyl pyrophosphate synthase(Human)
University of Illinois At Urbana-Champaign

Curated by ChEMBL
LigandPNGBDBM50135818([Phosphono-(pyridin-3-ylamino)-methyl]-phosphonic ...)
Affinity DataIC50: 158nMAssay Description:Inhibitory activity against farnesyl Pyrophosphate Synthase expressed as #NAME (M)More data for this Ligand-Target Pair
In Depth
Date in BDB:
11/10/2009
Entry Details Article
PubMed
TargetFarnesyl pyrophosphate synthase(Human)
University of Illinois At Urbana-Champaign

Curated by ChEMBL
LigandPNGBDBM50135818([Phosphono-(pyridin-3-ylamino)-methyl]-phosphonic ...)
Affinity DataKi:  15nMAssay Description:Binding affinity towards farnesyl Pyrophosphate Synthase using [14C]- isopentenyl pyrophosphate as radioligandMore data for this Ligand-Target Pair
In Depth
Date in BDB:
11/10/2009
Entry Details Article
PubMed