BDBM50135710 7,9-Dimethyl-1,4,5,6-tetrahydro-8-thia-1,2-diaza-cyclopenta[e]azulene::CHEMBL432579

SMILES Cc1sc(C)c-2c1CCCc1c[nH]nc-21

InChI Key InChIKey=YZKGQHRABFMYLD-UHFFFAOYSA-N

Data  9 KI  1 EC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
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Similarity at least:  must be >=0.5
Exact match

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 10 hits for monomerid = 50135710   

TargetD(4) dopamine receptor(Human)
Neurogen

Curated by ChEMBL
LigandPNGBDBM50135710(7,9-Dimethyl-1,4,5,6-tetrahydro-8-thia-1,2-diaza-c...)
Affinity DataEC50:  9nMAssay Description:Agonistic activity against human Dopamine receptor D4.2 using [35S]GTP-gamma-S binding assayMore data for this Ligand-Target Pair
In Depth
Date in BDB:
11/10/2009
Entry Details Article
PubMed
TargetD(4) dopamine receptor(Human)
Neurogen

Curated by ChEMBL
LigandPNGBDBM50135710(7,9-Dimethyl-1,4,5,6-tetrahydro-8-thia-1,2-diaza-c...)
Affinity DataKi:  12nMAssay Description:Binding affinity to recombinant human dopamine receptor D4More data for this Ligand-Target Pair
In Depth
Date in BDB:
11/10/2009
Entry Details Article
PubMed
Target5-hydroxytryptamine receptor 1A(Human)
Neurogen

Curated by ChEMBL
LigandPNGBDBM50135710(7,9-Dimethyl-1,4,5,6-tetrahydro-8-thia-1,2-diaza-c...)
Affinity DataKi: >1.00E+3nMAssay Description:Binding affinity towards cloned human 5-hydroxytryptamine 1A receptor was determinedMore data for this Ligand-Target Pair
In Depth
Date in BDB:
11/10/2009
Entry Details Article
PubMed
TargetD(2) dopamine receptor(Human)
Neurogen

Curated by ChEMBL
LigandPNGBDBM50135710(7,9-Dimethyl-1,4,5,6-tetrahydro-8-thia-1,2-diaza-c...)
Affinity DataKi:  2.07E+3nMAssay Description:Binding affinity towards cloned human Dopamine receptor D2 was determinedMore data for this Ligand-Target Pair
In Depth
Date in BDB:
11/10/2009
Entry Details Article
PubMed
TargetSerotonin 2 (5-HT2) receptor(Human)
Neurogen

Curated by ChEMBL
LigandPNGBDBM50135710(7,9-Dimethyl-1,4,5,6-tetrahydro-8-thia-1,2-diaza-c...)
Affinity DataKi:  2.09E+3nMAssay Description:Binding affinity towards cloned human 5-hydroxytryptamine 2 receptor was determinedMore data for this Ligand-Target Pair
In Depth
Date in BDB:
11/10/2009
Entry Details Article
PubMed
LigandPNGBDBM50135710(7,9-Dimethyl-1,4,5,6-tetrahydro-8-thia-1,2-diaza-c...)
Affinity DataKi: >7.80E+3nMAssay Description:Binding affinity towards cloned human Alpha-2 adrenergic receptor was determinedMore data for this Ligand-Target Pair
In Depth
Date in BDB:
11/10/2009
Entry Details Article
PubMed
TargetD(3) dopamine receptor(Human)
Neurogen

Curated by ChEMBL
LigandPNGBDBM50135710(7,9-Dimethyl-1,4,5,6-tetrahydro-8-thia-1,2-diaza-c...)
Affinity DataKi: >1.00E+4nMAssay Description:Binding affinity towards cloned human Dopamine receptor D3 was determinedMore data for this Ligand-Target Pair
In Depth
Date in BDB:
11/10/2009
Entry Details Article
PubMed
TargetD(1B) dopamine receptor(Human)
Neurogen

Curated by ChEMBL
LigandPNGBDBM50135710(7,9-Dimethyl-1,4,5,6-tetrahydro-8-thia-1,2-diaza-c...)
Affinity DataKi: >1.00E+4nMAssay Description:Binding affinity towards cloned human Dopamine receptor D5 was determinedMore data for this Ligand-Target Pair
In Depth
Date in BDB:
11/10/2009
Entry Details Article
PubMed
TargetD(1A) dopamine receptor(Human)
Neurogen

Curated by ChEMBL
LigandPNGBDBM50135710(7,9-Dimethyl-1,4,5,6-tetrahydro-8-thia-1,2-diaza-c...)
Affinity DataKi: >1.00E+4nMAssay Description:Binding affinity towards Dopamine receptor D1 was determinedMore data for this Ligand-Target Pair
In Depth
Date in BDB:
11/10/2009
Entry Details Article
PubMed
LigandPNGBDBM50135710(7,9-Dimethyl-1,4,5,6-tetrahydro-8-thia-1,2-diaza-c...)
Affinity DataKi: >1.00E+4nMAssay Description:Binding affinity towards cloned human Alpha-1 adrenergic receptor was determinedMore data for this Ligand-Target Pair
In Depth
Date in BDB:
11/10/2009
Entry Details Article
PubMed