BDBM50135667 3-(4-Naphthalen-2-ylmethyl-piperazin-1-ylmethyl)-pyrimido[5,4-e][1,2,4]triazine-5,7-diamine::CHEMBL318919

SMILES Nc1nc(N)c2nc(CN3CCN(Cc4ccc5ccccc5c4)CC3)nnc2n1

InChI Key InChIKey=SATYBAVYGUXQNB-UHFFFAOYSA-N

Data  2 IC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
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Similarity at least:  must be >=0.5
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Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 2 hits for monomerid = 50135667   

TargetTyrosine-protein phosphatase non-receptor type 1(Human)
Roche Research Center

Curated by ChEMBL
LigandPNGBDBM50135667(3-(4-Naphthalen-2-ylmethyl-piperazin-1-ylmethyl)-p...)
Affinity DataIC50: 3.30E+4nMAssay Description:Inhibition of Protein-tyrosine phosphatase 1B in 300 nM DTTMore data for this Ligand-Target Pair
In Depth
Date in BDB:
11/10/2009
Entry Details Article
PubMed
TargetTyrosine-protein phosphatase non-receptor type 1(Human)
Roche Research Center

Curated by ChEMBL
LigandPNGBDBM50135667(3-(4-Naphthalen-2-ylmethyl-piperazin-1-ylmethyl)-p...)
Affinity DataIC50: 3.50E+3nMAssay Description:Inhibition of Protein-tyrosine phosphatase 1B in 300 nM DTTMore data for this Ligand-Target Pair
In Depth
Date in BDB:
11/10/2009
Entry Details Article
PubMed