BDBM50135642 Benzo[b]thiophene-2-carboxylic acid (2-benzylsulfanyl-phenyl)-(3-dimethylamino-propyl)-amide::CHEMBL95501::N-(2-(benzylthio)phenyl)-N-(3-(dimethylamino)propyl)benzo[b]thiophene-2-carboxamide

SMILES CN(C)CCCN(C(=O)c1cc2ccccc2s1)c1ccccc1SCc1ccccc1

InChI Key InChIKey=JMYQNJICYNDYAT-UHFFFAOYSA-N

Data  6 IC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
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Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 6 hits for monomerid = 50135642   

TargetNeuropeptide Y receptor type 2(Human)
Bristol-Myers Squibb Pharmaceutical Research Institute

Curated by ChEMBL
LigandPNGBDBM50135642(N-(2-(benzylthio)phenyl)-N-(3-(dimethylamino)propy...)
Affinity DataIC50: 1.00E+3nMAssay Description:Binding affinity against SMS-KAN cell membranes endogenously expressing Neuropeptide Y receptor type 2 using [125I]PYY as radioligandMore data for this Ligand-Target Pair
In Depth
Date in BDB:
11/10/2009
Entry Details Article
PubMed
TargetNeuropeptide Y receptor type 2(Human)
Bristol-Myers Squibb Pharmaceutical Research Institute

Curated by ChEMBL
LigandPNGBDBM50135642(N-(2-(benzylthio)phenyl)-N-(3-(dimethylamino)propy...)
Affinity DataIC50: 450nMAssay Description:Binding affinity to neuropeptide Y2 receptorMore data for this Ligand-Target Pair
In Depth
Date in BDB:
8/26/2010
Entry Details Article
PubMed
TargetNeuropeptide Y receptor type 2(Human)
Bristol-Myers Squibb Pharmaceutical Research Institute

Curated by ChEMBL
LigandPNGBDBM50135642(N-(2-(benzylthio)phenyl)-N-(3-(dimethylamino)propy...)
Affinity DataIC50: 450nMAssay Description:Displacement of [125I]PYY from human NPY Y2 receptor expressed endogenously in KAN-Ts cells by scintillation countingMore data for this Ligand-Target Pair
In Depth
Date in BDB:
3/23/2012
Entry Details Article
PubMed
TargetNeuropeptide Y receptor type 2(Human)
Bristol-Myers Squibb Pharmaceutical Research Institute

Curated by ChEMBL
LigandPNGBDBM50135642(N-(2-(benzylthio)phenyl)-N-(3-(dimethylamino)propy...)
Affinity DataIC50: 1.00E+3nMAssay Description:Binding affinity against SMS-KAN cell membranes endogenously expressing Neuropeptide Y receptor type 2 using [125I]PYY as radioligandMore data for this Ligand-Target Pair
In Depth
Date in BDB:
11/10/2009
Entry Details Article
PubMed
TargetNeuropeptide Y receptor type 2(Human)
Bristol-Myers Squibb Pharmaceutical Research Institute

Curated by ChEMBL
LigandPNGBDBM50135642(N-(2-(benzylthio)phenyl)-N-(3-(dimethylamino)propy...)
Affinity DataIC50: 1.00E+3nMAssay Description:Binding affinity against SMS-KAN cell membranes endogenously expressing Neuropeptide Y receptor type 2 using [125I]PYY as radioligandMore data for this Ligand-Target Pair
In Depth
Date in BDB:
11/10/2009
Entry Details Article
PubMed
TargetNeuropeptide Y receptor type 2(Human)
Bristol-Myers Squibb Pharmaceutical Research Institute

Curated by ChEMBL
LigandPNGBDBM50135642(N-(2-(benzylthio)phenyl)-N-(3-(dimethylamino)propy...)
Affinity DataIC50: 1.00E+3nMAssay Description:Displacement of [125I]-PYY from NPYY2 receptor (unknown origin)More data for this Ligand-Target Pair
In Depth
Date in BDB:
7/25/2014
Entry Details Article
PubMed