BDBM50135599 (4S,5S,6S)-6-{(R)-Carbamoyl-[(2S,3S,4R,5R)-5-(2,4-dioxo-3,4-dihydro-2H-pyrimidin-1-yl)-4-hydroxy-3-methoxy-tetrahydro-furan-2-yl]-methoxy}-4,5-dihydroxy-5,6-dihydro-4H-pyran-2-carboxylic acid ((S)-2-oxo-azepan-3-yl)-amide::CHEMBL96695

SMILES CO[C@H]1[C@H]([C@@H](O[C@@H]1[C@H](C(=O)N)O[C@@H]2[C@H]([C@H](C=C(O2)C(=O)N[C@H]3CCCCNC3=O)O)O)N4C=CC(=O)NC4=O)O

InChI Key InChIKey=BISOEENGZHMDEO-UHFFFAOYSA-N

Data  5 IC50

PDB links: 1 PDB ID matches this monomer.

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
Find this compound or compounds like it in BindingDB:
   Substructure
Similarity at least:  must be >=0.5
Exact match

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 5 hits for monomerid = 50135599   

TargetPhospho-N-acetylmuramoyl-pentapeptide-transferase(Escherichia coli (strain K12))
Sankyo

Curated by ChEMBL
LigandPNGBDBM50135599((4S,5S,6S)-6-{(R)-Carbamoyl-[(2S,3S,4R,5R)-5-(2,4-...)
Affinity DataIC50: 18nMAssay Description:Inhibitory activity against translocase IMore data for this Ligand-Target Pair
In Depth
Date in BDB:
11/10/2009
Entry Details Article
PubMed
TargetPhospho-N-acetylmuramoyl-pentapeptide-transferase(Escherichia coli (strain K12))
Sankyo

Curated by ChEMBL
LigandPNGBDBM50135599((4S,5S,6S)-6-{(R)-Carbamoyl-[(2S,3S,4R,5R)-5-(2,4-...)
Affinity DataIC50: 18nMAssay Description:Inhibitory activity against translocase IMore data for this Ligand-Target Pair
In Depth
Date in BDB:
11/10/2009
Entry Details Article
PubMed
TargetPhospho-N-acetylmuramoyl-pentapeptide-transferase(Escherichia coli (strain K12))
Sankyo

Curated by ChEMBL
LigandPNGBDBM50135599((4S,5S,6S)-6-{(R)-Carbamoyl-[(2S,3S,4R,5R)-5-(2,4-...)
Affinity DataIC50: 17.6nMAssay Description:Inhibitory concentration against translocase-IMore data for this Ligand-Target Pair
In Depth
Date in BDB:
11/15/2018
Entry Details Article
PubMed
TargetUDP-N-acetylglucosamine--dolichyl-phosphate N-acetylglucosaminephosphotransferase(Human)
University of Tennessee Health Science Center

Curated by ChEMBL
LigandPNGBDBM50135599((4S,5S,6S)-6-{(R)-Carbamoyl-[(2S,3S,4R,5R)-5-(2,4-...)
Affinity DataIC50: 5.00E+4nMAssay Description:Inhibition of human DPAGT1 expressed in HEK293 (Expi293) cells incubated for 2 hrs using UDP-GlcN-Cg-FITC and alpha-dihydroundecap-renyl phosphate by...More data for this Ligand-Target Pair
In Depth
Date in BDB:
3/25/2022
Entry Details Article
PubMed
TargetPhospho-N-acetylmuramoyl-pentapeptide-transferase(Staphylococcus aureus)
Hokkaido University

Curated by ChEMBL
LigandPNGBDBM50135599((4S,5S,6S)-6-{(R)-Carbamoyl-[(2S,3S,4R,5R)-5-(2,4-...)
Affinity DataIC50: 330nMAssay Description:Inhibition of Staphylococcus aureus MraY assessed as reduction of dansylated lipid I formation using UDP-MurNAc-dansylpentapeptide as substrate incub...More data for this Ligand-Target Pair
In Depth
Date in BDB:
6/26/2023
Entry Details
PubMed