BDBM50135587 CHEMBL335994::{(S)-5-Benzo[1,3]dioxol-5-yl-3-[(S)-3-(3,4-difluoro-phenyl)-2-methyl-propionylamino]-2-oxo-2,3-dihydro-benzo[e][1,4]diazepin-1-yl}-acetic acid methyl ester

SMILES COC(=O)CN1c2ccccc2C(=N[C@H](NC(=O)[C@@H](C)Cc2ccc(F)c(F)c2)C1=O)c1ccc2OCOc2c1

InChI Key InChIKey=DJNHHASAPQZIRO-UHFFFAOYSA-N

Data  1 IC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
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Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 1 hit for monomerid = 50135587   

LigandPNGBDBM50135587({(S)-5-Benzo[1,3]dioxol-5-yl-3-[(S)-3-(3,4-difluor...)
Affinity DataIC50: 13nMAssay Description:In vitro inhibition of gamma secretase.More data for this Ligand-Target Pair
In Depth
Date in BDB:
11/10/2009
Entry Details Article
PubMed