BDBM50135576 (S)-N-[(S)-5-(2,2-Difluoro-benzo[1,3]dioxol-5-yl)-1-methyl-2-oxo-2,3-dihydro-1H-benzo[e][1,4]diazepin-3-yl]-3-(3,4-difluoro-phenyl)-2-methyl-propionamide::CHEMBL133235

SMILES C[C@@H](Cc1ccc(F)c(F)c1)C(=O)N[C@H]1N=C(c2ccc3OC(F)(F)Oc3c2)c2ccccc2N(C)C1=O

InChI Key InChIKey=WADIXAKIDBSZAJ-UHFFFAOYSA-N

Data  1 IC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
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Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 1 hit for monomerid = 50135576   

LigandPNGBDBM50135576((S)-N-[(S)-5-(2,2-Difluoro-benzo[1,3]dioxol-5-yl)-...)
Affinity DataIC50: 28nMAssay Description:In vitro inhibition of gamma secretase.More data for this Ligand-Target Pair
In Depth
Date in BDB:
11/10/2009
Entry Details Article
PubMed