BDBM50135535 3-{(R)-2-Cyano-2-[(S)-2-(1,1-dimethyl-3-oxo-1,3-dihydro-isobenzofuran-5-ylamino)-3-m-tolyl-propionylamino]-ethoxymethyl}-benzoic acid::CHEMBL131732

SMILES Cc1cccc(C[C@H](Nc2ccc3c(c2)C(=O)OC3(C)C)C(=O)N[C@@H](COCc2cccc(c2)C(O)=O)C#N)c1

InChI Key InChIKey=DJLOPBNMNYCRDV-UHFFFAOYSA-N

Data  3 IC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
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Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 3 hits for monomerid = 50135535   

TargetProcathepsin L(Human)
Novartis Institute of Biomedical Research

Curated by ChEMBL
LigandPNGBDBM50135535(3-{(R)-2-Cyano-2-[(S)-2-(1,1-dimethyl-3-oxo-1,3-di...)
Affinity DataIC50: 560nMAssay Description:Inhibitory activity against cathepsin L (catL)More data for this Ligand-Target Pair
In Depth
Date in BDB:
11/10/2009
Entry Details Article
PubMed
TargetCathepsin B(Human)
Novartis Institute of Biomedical Research

Curated by ChEMBL
LigandPNGBDBM50135535(3-{(R)-2-Cyano-2-[(S)-2-(1,1-dimethyl-3-oxo-1,3-di...)
Affinity DataIC50: 5.30nMAssay Description:Inhibitory activity against cathepsin B (catB)More data for this Ligand-Target Pair
In Depth
Date in BDB:
11/10/2009
Entry Details Article
PubMed
TargetCathepsin S(Human)
Novartis Institute of Biomedical Research

Curated by ChEMBL
LigandPNGBDBM50135535(3-{(R)-2-Cyano-2-[(S)-2-(1,1-dimethyl-3-oxo-1,3-di...)
Affinity DataIC50: 780nMAssay Description:Inhibitory activity against cathepsin S (catS)More data for this Ligand-Target Pair
In Depth
Date in BDB:
11/10/2009
Entry Details Article
PubMed