BDBM50135533 (S)-N-[(R)-Cyano-(3-tetrazol-1-yl-benzyloxymethyl)-methyl]-2-(3-oxo-1,3-dihydro-isobenzofuran-5-ylamino)-3-m-tolyl-propionamide::CHEMBL335426

SMILES Cc1cccc(C[C@H](Nc2ccc3COC(=O)c3c2)C(=O)N[C@@H](COCc2cccc(c2)-n2cnnn2)C#N)c1

InChI Key InChIKey=DREOLTOZTXSMOU-UHFFFAOYSA-N

Data  3 IC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
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Exact match

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 3 hits for monomerid = 50135533   

TargetCathepsin B(Human)
Novartis Institute of Biomedical Research

Curated by ChEMBL
LigandPNGBDBM50135533((S)-N-[(R)-Cyano-(3-tetrazol-1-yl-benzyloxymethyl)...)
Affinity DataIC50: 5nMAssay Description:Inhibitory activity against cathepsin B (catB)More data for this Ligand-Target Pair
In Depth
Date in BDB:
11/10/2009
Entry Details Article
PubMed
TargetCathepsin S(Human)
Novartis Institute of Biomedical Research

Curated by ChEMBL
LigandPNGBDBM50135533((S)-N-[(R)-Cyano-(3-tetrazol-1-yl-benzyloxymethyl)...)
Affinity DataIC50: 1.00E+3nMAssay Description:Inhibitory activity against cathepsin S (catS)More data for this Ligand-Target Pair
In Depth
Date in BDB:
11/10/2009
Entry Details Article
PubMed
TargetProcathepsin L(Human)
Novartis Institute of Biomedical Research

Curated by ChEMBL
LigandPNGBDBM50135533((S)-N-[(R)-Cyano-(3-tetrazol-1-yl-benzyloxymethyl)...)
Affinity DataIC50: 2.40E+3nMAssay Description:Inhibitory activity against cathepsin L (catL)More data for this Ligand-Target Pair
In Depth
Date in BDB:
11/10/2009
Entry Details Article
PubMed