BDBM50135494 4-(5-Fluoro-3-methyl-benzo[b]thiophene-2-sulfonylamino)-3-methanesulfonyl-benzoic acid methyl ester::CHEMBL129901

SMILES Cc1c2cc(ccc2sc1S(=O)(=O)Nc3ccc(cc3S(=O)(=O)C)C(=O)OC)F

InChI Key InChIKey=HQGLOZAWIWWMET-UHFFFAOYSA-N

Data  3 IC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
Find this compound or compounds like it in BindingDB:
   Substructure
Similarity at least:  must be >=0.5
Exact match

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 3 hits for monomerid = 50135494   

TargetChymase(Human)
Toa Eiyo

Curated by ChEMBL
LigandPNGBDBM50135494(4-(5-Fluoro-3-methyl-benzo[b]thiophene-2-sulfonyla...)
Affinity DataIC50: 56nMAssay Description:In vitro inhibitory activity against human chymaseMore data for this Ligand-Target Pair
In Depth
Date in BDB:
11/10/2009
Entry Details Article
PubMed
TargetCathepsin G(Human)
Toa Eiyo

Curated by ChEMBL
LigandPNGBDBM50135494(4-(5-Fluoro-3-methyl-benzo[b]thiophene-2-sulfonyla...)
Affinity DataIC50: 1.00E+3nMAssay Description:In vitro inhibitory activity against human cathepsin GMore data for this Ligand-Target Pair
In Depth
Date in BDB:
11/10/2009
Entry Details Article
PubMed
TargetChymotrypsin-C(Human)
Toa Eiyo

Curated by ChEMBL
LigandPNGBDBM50135494(4-(5-Fluoro-3-methyl-benzo[b]thiophene-2-sulfonyla...)
Affinity DataIC50: 1.00E+3nMAssay Description:In vitro inhibitory activity against bovin chymotrypsinMore data for this Ligand-Target Pair
In Depth
Date in BDB:
11/10/2009
Entry Details Article
PubMed