BDBM50135384 5-(3-Chloro-2-fluoro-phenyl)-6-[(4-cyano-phenyl)-(3-methyl-3H-imidazol-4-yl)-methoxymethyl]-1-methyl-2-oxo-1,2-dihydro-pyridine-3-carbonitrile::CHEMBL336569

SMILES Cn1cncc1C(OCc1c(cc(C#N)c(=O)n1C)-c1cccc(Cl)c1F)c1ccc(cc1)C#N

InChI Key InChIKey=MILFHOSIWZCDMY-UHFFFAOYSA-N

Data  2 IC50  1 EC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
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Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 3 hits for monomerid = 50135384   

LigandPNGBDBM50135384(5-(3-Chloro-2-fluoro-phenyl)-6-[(4-cyano-phenyl)-(...)
Affinity DataIC50: 1.80nMAssay Description:In vitro inhibitory activity against farnesyltransferase (FT)More data for this Ligand-Target Pair
In Depth
Date in BDB:
11/10/2009
Entry Details Article
PubMed
LigandPNGBDBM50135384(5-(3-Chloro-2-fluoro-phenyl)-6-[(4-cyano-phenyl)-(...)
Affinity DataEC50:  24nMAssay Description:In vitro effective concentration against farnesyltransferase (FT)More data for this Ligand-Target Pair
In Depth
Date in BDB:
11/10/2009
Entry Details Article
PubMed
LigandPNGBDBM50135384(5-(3-Chloro-2-fluoro-phenyl)-6-[(4-cyano-phenyl)-(...)
Affinity DataIC50: 1.50E+3nMAssay Description:In vitro inhibitory activity against Geranylgeranyl transferase type IMore data for this Ligand-Target Pair
In Depth
Date in BDB:
11/10/2009
Entry Details Article
PubMed