BDBM50135357 6-[(4-Cyano-phenyl)-thiazol-5-yl-methoxymethyl]-5-(3,5-dichloro-phenyl)-1-methyl-2-oxo-1,2-dihydro-pyridine-3-carbonitrile::CHEMBL128572

SMILES Cn1c(COC(c2cncs2)c2ccc(cc2)C#N)c(cc(C#N)c1=O)-c1cc(Cl)cc(Cl)c1

InChI Key InChIKey=RDRLCMALXVPSHH-UHFFFAOYSA-N

Data  2 IC50  1 EC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
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Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 3 hits for monomerid = 50135357   

LigandPNGBDBM50135357(6-[(4-Cyano-phenyl)-thiazol-5-yl-methoxymethyl]-5-...)
Affinity DataIC50: 1.90nMAssay Description:In vitro inhibitory activity against farnesyltransferase (FT)More data for this Ligand-Target Pair
In Depth
Date in BDB:
11/10/2009
Entry Details Article
PubMed
LigandPNGBDBM50135357(6-[(4-Cyano-phenyl)-thiazol-5-yl-methoxymethyl]-5-...)
Affinity DataEC50: >100nMAssay Description:In vitro effective concentration against farnesyltransferase (FT)More data for this Ligand-Target Pair
In Depth
Date in BDB:
11/10/2009
Entry Details Article
PubMed
LigandPNGBDBM50135357(6-[(4-Cyano-phenyl)-thiazol-5-yl-methoxymethyl]-5-...)
Affinity DataIC50: 1.00E+4nMAssay Description:In vitro inhibitory activity against Geranylgeranyl transferase type IMore data for this Ligand-Target Pair
In Depth
Date in BDB:
11/10/2009
Entry Details Article
PubMed