BDBM50135239 (S)-1-[(2R,4S)-4-(4-Methoxy-benzo[b]thiophen-2-yl)-2-methyl-piperidin-1-yl]-3-(2-methyl-1H-indol-4-yloxy)-propan-2-ol::CHEMBL338298

SMILES COc1cccc2sc(cc12)[C@H]1CCN(C[C@H](O)COc2cccc3[nH]c(C)cc23)[C@H](C)C1

InChI Key InChIKey=MBTNZOCGXGVNLT-UHFFFAOYSA-N

Data  2 KI

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
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Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 2 hits for monomerid = 50135239   

TargetSodium-dependent serotonin transporter(Rat)
Eli Lilly

Curated by ChEMBL
LigandPNGBDBM50135239((S)-1-[(2R,4S)-4-(4-Methoxy-benzo[b]thiophen-2-yl)...)
Affinity DataKi:  3.30nMAssay Description:Affinity at the 5-HT reuptake site labeled with [3H]paroxetine using rat frontal cortex membranesMore data for this Ligand-Target Pair
In Depth
Date in BDB:
11/10/2009
Entry Details Article
PubMed
Target5-hydroxytryptamine receptor 1A(Human)
Eli Lilly

Curated by ChEMBL
LigandPNGBDBM50135239((S)-1-[(2R,4S)-4-(4-Methoxy-benzo[b]thiophen-2-yl)...)
Affinity DataKi:  28nMAssay Description:Binding affinity towards 5-hydroxytryptamine 1A receptor in human using [3H]8-OH-DPAT as radioligandMore data for this Ligand-Target Pair
In Depth
Date in BDB:
11/10/2009
Entry Details Article
PubMed