BDBM50134986 CHEMBL3746559

SMILES NC(=O)c1c(Oc2ccc(F)c(NS(N)(=O)=O)c2)cc(F)c(F)c1Nc1ccc(I)cc1F

InChI Key InChIKey=LTQRQYGKFXIKSB-UHFFFAOYSA-N

Data  2 IC50

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 2 hits for monomerid = 50134986   

TargetDual specificity mitogen-activated protein kinase kinase 1(Human)
Bayer Healthcare

Curated by ChEMBL

LigandBDBM50134986(CHEMBL3746559)Copy SMILESCopy InChI

Affinity DataIC50: 14nMAssay Description:Inhibition of MEK1 (unknown origin) using biotinylated ERK1 as substrate incubated for 2 hrs by fluorescence analysisMore data for this Ligand-Target Pair

Target InfoPDBKEGG
UniProtKB/SwissProt
GoogleScholar

Ligand InfoCHEMBLPC cidPC sidSimilars

In Depth
Date in BDB:
5/26/2017
Entry Details Article
Copy Entry DOIPubMed
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TargetCarbonic anhydrase 2(Human)
Bayer Healthcare

Curated by ChEMBL

LigandBDBM50134986(CHEMBL3746559)Copy SMILESCopy InChI

Affinity DataIC50: 4.60E+3nMAssay Description:Inhibition of human carbonic anhydrase 2More data for this Ligand-Target Pair

Target InfoPDBKEGG
UniProtKB/SwissProt
GoogleScholar

Ligand InfoCHEMBLPC cidPC sidSimilars

In Depth
Date in BDB:
5/26/2017
Entry Details Article
Copy Entry DOIPubMed
Copy Rxn URL