BDBM50134979 (2-(3-(4-(4-fluorophenyl)piperazin-1-yl)-2-hydroxypropoxy)phenyl)(phenyl)methanone::(2-{3-[4-(4-Fluoro-phenyl)-piperazin-1-yl]-2-hydroxy-propoxy}-phenyl)-phenyl-methanone::CHEMBL148318

SMILES OC(COc1ccccc1C(=O)c1ccccc1)CN1CCN(CC1)c1ccc(F)cc1

InChI Key InChIKey=UHWBVAVSBQYTQW-UHFFFAOYSA-N

Data  1 IC50  1 EC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
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Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 2 hits for monomerid = 50134979   

TargetATP-dependent translocase ABCB1(Human)
University of Vienna

Curated by ChEMBL
LigandPNGBDBM50134979((2-(3-(4-(4-fluorophenyl)piperazin-1-yl)-2-hydroxy...)
Affinity DataEC50:  147nMAssay Description:Inhibition of P-glycoprotein expressed in MDR CCRF vcr1000 cells by daunorubicin efflux assayMore data for this Ligand-Target Pair
In Depth
Date in BDB:
12/9/2012
Entry Details Article
PubMed
TargetATP-dependent translocase ABCB1(Human)
University of Vienna

Curated by ChEMBL
LigandPNGBDBM50134979((2-(3-(4-(4-fluorophenyl)piperazin-1-yl)-2-hydroxy...)
Affinity DataIC50: 150nMAssay Description:Inhibition of P-glycoprotein-mediated daunorubicin efflux from human CCRF-CEM/VCR1000 cells after 240 secs by FACS flow cytometric analysisMore data for this Ligand-Target Pair
In Depth
Date in BDB:
8/29/2020
Entry Details Article
PubMed