BDBM50134969 CHEMBL3746923

SMILES NC(=O)c1c(Nc2ccc(I)cc2F)cc(F)cc1Oc1cccc(CNS(N)(=O)=O)c1

InChI Key InChIKey=SGVLAJYAPDCHSS-UHFFFAOYSA-N

Data  2 IC50

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 2 hits for monomerid = 50134969   

TargetDual specificity mitogen-activated protein kinase kinase 1(Human)
Bayer Healthcare

Curated by ChEMBL

LigandBDBM50134969(CHEMBL3746923)Copy SMILESCopy InChI

Affinity DataIC50: 37nMAssay Description:Inhibition of MEK1 (unknown origin) using biotinylated ERK1 as substrate incubated for 2 hrs by fluorescence analysisMore data for this Ligand-Target Pair

Target InfoPDBKEGG
UniProtKB/SwissProt
GoogleScholar

Ligand InfoCHEMBLPC cidPC sidSimilars

In Depth
Date in BDB:
5/26/2017
Entry Details Article
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TargetCarbonic anhydrase 2(Human)
Bayer Healthcare

Curated by ChEMBL

LigandBDBM50134969(CHEMBL3746923)Copy SMILESCopy InChI

Affinity DataIC50: 2.80E+3nMAssay Description:Inhibition of human carbonic anhydrase 2More data for this Ligand-Target Pair

Target InfoPDBKEGG
UniProtKB/SwissProt
GoogleScholar

Ligand InfoCHEMBLPC cidPC sidSimilars

In Depth
Date in BDB:
5/26/2017
Entry Details Article
Copy Entry DOIPubMed
Copy Rxn URL