BDBM50134961 CHEMBL3746142

SMILES NC(=O)c1c(Nc2ccc(I)cc2F)cc(F)cc1Oc1ccccc1NS(N)(=O)=O

InChI Key InChIKey=JOJMSCKMPKOSOQ-UHFFFAOYSA-N

Data  2 IC50

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 2 hits for monomerid = 50134961   

TargetDual specificity mitogen-activated protein kinase kinase 1(Human)
Bayer Healthcare

Curated by ChEMBL

LigandBDBM50134961(CHEMBL3746142)Copy SMILESCopy InChI

Affinity DataIC50: 81nMAssay Description:Inhibition of MEK1 (unknown origin) using biotinylated ERK1 as substrate incubated for 2 hrs by fluorescence analysisMore data for this Ligand-Target Pair

Target InfoPDBKEGG
UniProtKB/SwissProt
GoogleScholar

Ligand InfoCHEMBLPC cidPC sidSimilars

In Depth
Date in BDB:
5/26/2017
Entry Details Article
Copy Entry DOIPubMed
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TargetCarbonic anhydrase 2(Human)
Bayer Healthcare

Curated by ChEMBL

LigandBDBM50134961(CHEMBL3746142)Copy SMILESCopy InChI

Affinity DataIC50: 500nMAssay Description:Inhibition of human carbonic anhydrase 2More data for this Ligand-Target Pair

Target InfoPDBKEGG
UniProtKB/SwissProt
GoogleScholar

Ligand InfoCHEMBLPC cidPC sidSimilars

In Depth
Date in BDB:
5/26/2017
Entry Details Article
Copy Entry DOIPubMed
Copy Rxn URL