BDBM50134911 4-[1,3]Dioxolo[4,5-g]quinazolin-8-yl-piperazine-1-carboxylic acid (4-phenoxy-phenyl)-amide::CHEMBL144749

SMILES O=C(Nc1ccc(Oc2ccccc2)cc1)N1CCN(CC1)c1ncnc2cc3OCOc3cc12

InChI Key InChIKey=KNFLTOWBYQEOPM-UHFFFAOYSA-N

Data  1 IC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
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Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 1 hit for monomerid = 50134911   

TargetPlatelet-derived growth factor receptor beta(Human)
Pharmaceutical Research Institute

Curated by ChEMBL
LigandPNGBDBM50134911(4-[1,3]Dioxolo[4,5-g]quinazolin-8-yl-piperazine-1-...)
Affinity DataIC50: 90nMAssay Description:Inhibition of platelet-derived growth factor receptor beta phosphorylation was measured in intact cells using a two-site enzyme linked immunosorbent ...More data for this Ligand-Target Pair
In Depth
Date in BDB:
11/10/2009
Entry Details Article
PubMed