BDBM50134858 4-(7-Methoxy-6-prop-2-ynyloxy-quinazolin-4-yl)-piperazine-1-carboxylic acid (4-phenoxy-phenyl)-amide::CHEMBL448729

SMILES COc1cc2ncnc(N3CCN(CC3)C(=O)Nc3ccc(Oc4ccccc4)cc3)c2cc1OCC#C

InChI Key InChIKey=UXCTZAPHINPHDD-UHFFFAOYSA-N

Data  1 IC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
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Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 1 hit for monomerid = 50134858   

TargetPlatelet-derived growth factor receptor beta(Human)
Pharmaceutical Research Institute

Curated by ChEMBL
LigandPNGBDBM50134858(4-(7-Methoxy-6-prop-2-ynyloxy-quinazolin-4-yl)-pip...)
Affinity DataIC50: 60nMAssay Description:Inhibition of platelet-derived growth factor receptor beta phosphorylation was measured in intact cells using a two-site enzyme linked immunosorbent ...More data for this Ligand-Target Pair
In Depth
Date in BDB:
11/10/2009
Entry Details Article
PubMed