BDBM50134836 6-tert-Butoxy-4-(4-fluoro-phenyl)-3-(4-methanesulfonyl-phenyl)-pyran-2-one::CHEMBL146009

SMILES CC(C)(C)Oc1cc(-c2ccc(F)cc2)c(-c2ccc(cc2)S(C)(=O)=O)c(=O)o1

InChI Key InChIKey=XTCVYOHPHOELRF-UHFFFAOYSA-N

Data  2 IC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
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Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 2 hits for monomerid = 50134836   

TargetProstaglandin G/H synthase 2(Bovine)
University of Alberta

Curated by ChEMBL
LigandPNGBDBM50134836(6-tert-Butoxy-4-(4-fluoro-phenyl)-3-(4-methanesulf...)
Affinity DataIC50: 2.04E+4nMAssay Description:In vitro inhibitory activity against prostaglandin G/H synthase 2 (COX-2)More data for this Ligand-Target Pair
In Depth
Date in BDB:
11/30/2012
Entry Details Article
PubMed
TargetProstaglandin G/H synthase 1(Sheep)
University of Alberta

Curated by ChEMBL
LigandPNGBDBM50134836(6-tert-Butoxy-4-(4-fluoro-phenyl)-3-(4-methanesulf...)
Affinity DataIC50: 6.85E+4nMAssay Description:In vitro inhibitory activity against Prostaglandin G/H synthase 1 (COX-1)More data for this Ligand-Target Pair
In Depth
Date in BDB:
11/30/2012
Entry Details Article
PubMed