BDBM50134799 6-((5S,8S,11S,13aR)-5,8-Dimethyl-4,7,10,13-tetraoxo-tetradecahydro-3a,6,9,12-tetraaza-cyclopentacyclododecen-11-yl)-hexanoic acid hydroxyamide::CHEMBL145110

SMILES C[C@@H]1NC(=O)[C@H](CCCCCC(=O)NO)NC(=O)[C@H]2CCCN2C(=O)[C@H](C)NC1=O

InChI Key InChIKey=ICSUPTZKVJGDQG-UHFFFAOYSA-N

Data  1 IC50  2 EC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
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Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 3 hits for monomerid = 50134799   

TargetHistone deacetylase 4(Human)
Sapienza University of Rome

Curated by ChEMBL
LigandPNGBDBM50134799(6-((5S,8S,11S,13aR)-5,8-Dimethyl-4,7,10,13-tetraox...)
Affinity DataIC50: 2.70nMAssay Description:Inhibition of Histone deacetylase 4 in mammalian cells.More data for this Ligand-Target Pair
In Depth
Date in BDB:
11/30/2012
Entry Details Article
PubMed
TargetHistone deacetylase 6(Human)
Sapienza University of Rome

Curated by ChEMBL
LigandPNGBDBM50134799(6-((5S,8S,11S,13aR)-5,8-Dimethyl-4,7,10,13-tetraox...)
Affinity DataEC50:  1.90E+4nMAssay Description:Tested for inhibition of Histone deacetylase 6 induced acetylated tubulin in mammalian cells.More data for this Ligand-Target Pair
In Depth
Date in BDB:
11/30/2012
Entry Details Article
PubMed
TargetHistone deacetylase 1(Human)
Sapienza University of Rome

Curated by ChEMBL
LigandPNGBDBM50134799(6-((5S,8S,11S,13aR)-5,8-Dimethyl-4,7,10,13-tetraox...)
Affinity DataEC50:  1.90E+3nMAssay Description:Inhibition of Histone deacetylase 1 induced acetylated histone in mammalian cells.More data for this Ligand-Target Pair
In Depth
Date in BDB:
11/30/2012
Entry Details Article
PubMed