BDBM50134706 5-{2-[4-(2-Biphenyl-2-yl-2-hydroxy-acetylamino)-5-(3,5-difluoro-phenyl)-3-hydroxy-pentanoylamino]-3-methyl-butyrylamino}-isophthalic acid::CHEMBL143239

SMILES CC(C)[C@H](NC(=O)C[C@H](O)[C@H](Cc1cc(F)cc(F)c1)NC(=O)C(O)c1ccccc1-c1ccccc1)C(=O)Nc1cc(cc(c1)C(O)=O)C(O)=O

InChI Key InChIKey=CHXMXMUUGTWIEN-UHFFFAOYSA-N

Data  1 IC50  1 EC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
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Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 2 hits for monomerid = 50134706   

TargetBeta-secretase 1(Human)
Elan Pharmaceuticals

Curated by ChEMBL
LigandPNGBDBM50134706(5-{2-[4-(2-Biphenyl-2-yl-2-hydroxy-acetylamino)-5-...)
Affinity DataIC50: 20nMAssay Description:Compound was tested for its inhibitory activity against human beta-Secretase (BACE)More data for this Ligand-Target Pair
In Depth
Date in BDB:
11/10/2009
Entry Details Article
PubMed
TargetBeta-secretase 1(Human)
Elan Pharmaceuticals

Curated by ChEMBL
LigandPNGBDBM50134706(5-{2-[4-(2-Biphenyl-2-yl-2-hydroxy-acetylamino)-5-...)
Affinity DataEC50:  1.00E+4nMAssay Description:Compound was tested for its effective concentration against human beta-Secretase (BACE)More data for this Ligand-Target Pair
In Depth
Date in BDB:
11/10/2009
Entry Details Article
PubMed